Talk:Carbamate

Latest comment: 1 year ago by Theheathbar01 in topic Wiki Education assignment: Toxicology

Untitled edit

I removed the hyperlink in "carbamic acid" because it redirected to the same page (carbamate)Hnc 06:50, 9 December 2006 (UTC)Reply

It is not accurate to say that K<<1 for the carboxylation of an amine because the C-N bond is labile. K<<1 is a statement of thermodynamics which suggests that the amine and the fully oxidized CO2 are more stable than the carbamate product. Suggesting that the C-N bond is labile is a statement of its kinetics, meaning that it takes little energy to get to this reaction's transition state. I imagine the author meant to say that the C-N bond is less stable. — Preceding unsigned comment added by 18.74.5.212 (talk) 23:16, 13 December 2006 (UTC)Reply

terminal carbamic acids edit

I believe carbamic acids in themselves are unstable, never mind if the amine is alkylated or not... John Riemann Soong (talk) 03:51, 24 March 2010 (UTC)Reply

Some carbamic acids have been isolated and even had their crystal structures determined: Chem. Commun. (2000), 1099-1100.
Ben (talk) 10:43, 24 March 2010 (UTC)Reply

I take issue with the sentence that states carbamate esters are reversible inhibitors of acetylcholinesterase. They actually carbamoylate the active site serine in an analogous manner to phosphorus esters, which phosphorylate the same serine residue. However, although the carbamoylated group is hydrolysed at a faster rate than phosphorylated serine, they are still not reversible inhibitors in the strict sense.81.151.231.65 (talk) 18:16, 12 November 2012 (UTC)Philip JewessReply

Wiki Education assignment: Toxicology edit

  This article was the subject of a Wiki Education Foundation-supported course assignment, between 10 August 2022 and 8 December 2022. Further details are available on the course page. Student editor(s): Rachael.kateee (article contribs).

— Assignment last updated by Theheathbar01 (talk) 18:06, 17 September 2022 (UTC)Reply