RRP9

U3 small nucleolar RNA-interacting protein 2 is a protein that in humans is encoded by the RRP9 gene.

RRP9
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4J0W, 4JXM
Identifiers
Aliases	RRP9, RNU3IP2, U3-55K, ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast), ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
External IDs	MGI: 2384313 HomoloGene: 3452 GeneCards: RRP9
Gene location (Human) Chr. Chromosome 3 (human) Band 3p21.2 Start 51,933,429 bp End 51,941,904 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9 F1|9 57.59 cM Start 106,353,162 bp End 106,362,623 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle left uterine tube right adrenal gland upper lobe of left lung skin of abdomen tibial nerve left coronary artery canal of the cervix right lobe of thyroid gland body of stomach Top expressed in yolk sac morula entorhinal cortex spermatocyte spermatid lip primitive streak superior frontal gyrus neural tube visual cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function U3 snoRNA binding RNA binding snoRNA binding Cellular component small-subunit processome nucleolus box C/D RNP complex nucleoplasm nucleus Biological process rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9136 27966 Ensembl ENSG00000114767 ENSMUSG00000041506 UniProt O43818 Q91WM3 RefSeq (mRNA) NM_004704 NM_145620 RefSeq (protein) NP_004695 NP_663595 Location (UCSC) Chr 3: 51.93 – 51.94 Mb Chr 9: 106.35 – 106.36 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

See also

• Fibrillarin
• Small nucleolar RNA U3
• RCL1
• RRP9
• UTP6
• UTP11L
• UTP14A
• UTP15

Further reading

• Lukowiak AA, Granneman S, Mattox SA, Speckmann WA, Jones K, Pluk H, et al. (2000). "Interaction of the U3-55k protein with U3 snoRNA is mediated by the Box B/C motif of U3 and the WD repeats of U3-55k". Nucleic Acids Res. 28 (18): 3462–71. doi:10.1093/nar/28.18.3462. PMC 110750. PMID 10982864.
• Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
• Granneman S, Pruijn GJ, Horstman W, Van Venrooij WJ, Luhrmann R, Watkins NJ (2003). "The hU3-55K protein requires 15.5K binding to the box B/C motif as well as flanking RNA elements for its association with the U3 small nucleolar RNA in Vitro". J. Biol. Chem. 277 (50): 48490–500. doi:10.1074/jbc.M206631200. hdl:11858/00-001M-0000-0012-F261-B. PMID 12381732.
• Scherl A, Couté Y, Déon C, Callé A, Kindbeiter K, Sanchez JC, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
• Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Watkins NJ, Lemm I, Ingelfinger D, Schneider C, Hoßbach M, Urlaub H, et al. (2005). "Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex". Mol. Cell. 16 (5): 789–98. doi:10.1016/j.molcel.2004.11.012. hdl:11858/00-001M-0000-0012-EB89-8. PMID 15574333.
• Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
• Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788.
• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human U3 small nucleolar RNA-interacting protein 2 (RRP9)