Diede de Groot defeated the two-time defending champion Yui Kamiji in the final, 6–1, 6–0 to win the women's singles wheelchair tennis title at the 2019 French Open. With the win, de Groot completed a non-calendar-year Grand Slam and the career Grand Slam, becoming the first wheelchair tennis player to do each in singles.
| Wheelchair women's singles | |
|---|---|
| 2019 French Open | |
| Champion |  Diede de Groot |
| Runner-up |  Yui Kamiji |
| Score | 6–1, 6–0 |
Seeds edit
Diede de Groot (champion)
Yui Kamiji (final)
Draw edit
Key edit
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- SE = Special exempt
- PR = Protected ranking
- ITF = ITF entry
- JE = Junior exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
- SR = Special ranking
Finals edit
| Quarterfinals | Semifinals | Final | ||||||||||||||||||
| 1 | Diede de Groot
| 6 | 6 | |||||||||||||||||
 Kgothatso Montjane
| 1 | 0 | ||||||||||||||||||
| 1 | Diede de Groot
| 6 | 65 | 6 | ||||||||||||||||
| Aniek van Koot
| 4 | 77 | 4 | |||||||||||||||||
| Aniek van Koot
| 6 | 6 | ||||||||||||||||||
 Sabine Ellerbrock
| 1 | 1 | ||||||||||||||||||
| 1 | Diede de Groot
| 6 | 6 | |||||||||||||||||
| 2 | Yui Kamiji
| 1 | 0 | |||||||||||||||||
| WC |  Charlotte Famin
| 1 | 0 | |||||||||||||||||
| Marjolein Buis
| 6 | 6 | ||||||||||||||||||
| Marjolein Buis
| 4 | 5 | ||||||||||||||||||
| 2 | Yui Kamiji
| 6 | 7 | |||||||||||||||||
 Giulia Capocci
| 4 | 2 | ||||||||||||||||||
| 2 | Yui Kamiji
| 6 | 6 | |||||||||||||||||