Defending champion Yui Kamiji defeated Diede de Groot in the final, 2–6, 6–0, 6–2 to win the women's singles wheelchair tennis title at the 2018 French Open. It was de Groot's only loss at the majors that year, preventing her from achieving the Grand Slam.
| Wheelchair women's singles | |
|---|---|
| 2018 French Open | |
| Champion |  Yui Kamiji |
| Runner-up |  Diede de Groot |
| Score | 2–6, 6–0, 6–2 |
Seeds edit
Yui Kamiji (champion)
Diede de Groot (final)
Draw edit
Key edit
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- SE = Special exempt
- PR = Protected ranking
- ITF = ITF entry
- JE = Junior exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
- SR = Special ranking
Finals edit
| Quarterfinals | Semifinals | Final | ||||||||||||||||||
| 1 | Yui Kamiji
| 6 | 6 | |||||||||||||||||
| WC |  Charlotte Famin
| 1 | 2 | |||||||||||||||||
| 1 | Yui Kamiji
| 6 | 710 | |||||||||||||||||
| Aniek van Koot
| 3 | 68 | ||||||||||||||||||
| Aniek van Koot
| 6 | 3 | 6 | |||||||||||||||||
 Kgothatso Montjane
| 1 | 6 | 1 | |||||||||||||||||
| 1 | Yui Kamiji
| 2 | 6 | 6 | ||||||||||||||||
| 2 | Diede de Groot
| 6 | 0 | 2 | ||||||||||||||||
 Sabine Ellerbrock
| 6 | 7 | ||||||||||||||||||
| Katharina Krüger
| 2 | 5 | ||||||||||||||||||
| Sabine Ellerbrock
| 3 | 1 | ||||||||||||||||||
| 2 | Diede de Groot
| 6 | 6 | |||||||||||||||||
| Marjolein Buis
| 2 | 0 | ||||||||||||||||||
| 2 | Diede de Groot
| 6 | 6 | |||||||||||||||||