Zinc finger protein 296

Zinc finger protein 296 is a protein that in humans is encoded by the ZNF296 gene.

ZNF296
Identifiers
Aliases	ZNF296, ZFP296, ZNF342, zinc finger protein 296
External IDs	OMIM: 613226; MGI: 1926956; HomoloGene: 11185; GeneCards: ZNF296; OMA:ZNF296 - orthologs
Gene location (Human) Chr. Chromosome 19 (human) Band 19q13.32 Start 45,071,500 bp End 45,076,478 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 A3 Start 19,311,212 bp End 19,314,581 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad granulocyte nasal epithelium monocyte testicle mucosa of transverse colon blood skin of abdomen parotid gland spleen Top expressed in primary oocyte zygote secondary oocyte morula blastocyst granulocyte right ventricle hair follicle lip embryo More reference expression data BioGPS n/a
Gene ontology Molecular function metal ion binding nucleic acid binding molecular function DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity sequence-specific DNA binding transcription factor binding Cellular component nucleus cellular component Biological process negative regulation of transcription by RNA polymerase II transcription, DNA-templated regulation of transcription, DNA-templated spermatogenesis positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 162979 63872 Ensembl ENSG00000170684 ENSMUSG00000011267 UniProt Q8WUU4 E9Q6W4 RefSeq (mRNA) NM_145288 NM_022409 RefSeq (protein) NP_660331 NP_071854 Location (UCSC) Chr 19: 45.07 – 45.08 Mb Chr 7: 19.31 – 19.31 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Poland KS, Shardy DL, Azim M, Naeem R, Krance RA, Dreyer ZE, Neeley ES, Zhang N, Qiu YH, Kornblau SM, Plon SE (2009). "Overexpression of ZNF342 by juxtaposition with MPO promoter/enhancer in the novel translocation t(17;19)(q23;q13.32) in pediatric acute myeloid leukemia and analysis of ZNF342 expression in leukemia". Genes Chromosomes Cancer. 48 (6): 480–9. doi:10.1002/gcc.20654. PMC 3385932. PMID 19255975.
• Matsuura T, Miyazaki S, Miyazaki T, Tashiro F, Miyazaki JI (2017). "Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin". Scientific Reports. 7 (1): 12462. Bibcode:2017NatSR...712462M. doi:10.1038/s41598-017-12772-y. PMC 5622089. PMID 28963472.