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Zephyr Surgical Implants (ZSI) is a Swiss-based medical device manufacturer that produces and distributes artificial urinary sphincters and penile implants worldwide. ZSI products are used in the management of moderate-to-severe urinary incontinence in men, erectile dysfunction, Peyronie's disease, penis enlargement, and female-to-male gender reassignment surgery.
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| Company type | Private |
|---|---|
| Industry | Health care |
| Founded | 2005 |
| Founder | Christophe Llorens (CEO) |
| Headquarters | Geneva (GE), Switzerland |
Area served | Worldwide |
Key people | Raphael Llorens |
| Website | zsimplants |
History edit
The company was founded by Dr. Christophe Llorens and Raphael Llorens in 2005.[1] The first product – ZSI 375 artificial urinary sphincter, was introduced in 2009.[2][3] As of 2019, more than 4500 ZSI 375 artificial urinary sphincters were implanted worldwide.[2] The inflatable penile implant designed for female-to-male gender reassignment surgeries became available in the European market in March 2016, and the first phalloplasty procedures using ZSI 475 FtM implants were performed in June 2016.[4]
Many clinical studies have been performed with the artificial urinary sphincter ZSI 375 in the treatment of moderate and severe stress incontinence, most of them are retrospective and non-randomized tests. Success rates in total or social continence vary, in a period of 6 to 24 months, between 68 and 89%.[5][6]
References edit
- ^ Vakalopoulos, Ioannis; Kampantais, Spyridon; Laskaridis, Leonidas; Chachopoulos, Vasileios; Koptsis, Michail; Toutziaris, Chrysovalantis (2012). "New Artificial Urinary Sphincter Devices in the Treatment of Male Iatrogenic Incontinence". Advances in Urology. 2012 (Special Issue): 439372. doi:10.1155/2012/439372. PMC 3332164. PMID 22567002.
- ^ a b Zephyr Surgical Implants (November 2019). ARTIFICIAL URINARY SPHINCTER ZSI 375 (PDF) (Second ed.). Geneva, Switzerland: Zephyr Surgical Implants. Retrieved 19 January 2020.
- ^ Amend, Bastian; Toomey, Patricia; Sievert, Karl-Dietrich (2013). "Artificial sphincter". Current Opinion in Urology. 23 (6): 520–527. doi:10.1097/01.MOU.0000434591.02823.d0. PMID 24080811. S2CID 207858515. Retrieved 19 January 2020.
- ^ Neuville, Paul; Morel-Journel, Nicolas; Cabelguenne, Delphine; Ruffion, Alain; Paparel, Philippe; Terrier, Jean-Etienne (2019). "First Outcomes of the ZSI 475 FtM, a Specific Prosthesis Designed for Phalloplasty". The Journal of Sexual Medicine. 16 (2): 316–322. doi:10.1016/j.jsxm.2018.11.013. PMID 30638882. Retrieved 19 January 2020.
- ^ Staerman, Frederic; G-Llorens, Christophe; Leon, Priscilla; Leclerc, Yves (April 2013). "ZSI 375 artificial urinary sphincter for male urinary incontinence: a preliminary study: ZSI 375 AUS: PRELIMINARY STUDY". BJU International. 111 (4b): E202–E206. doi:10.1111/j.1464-410X.2012.11468.x. PMID 22937774. S2CID 7963443.
- ^ "Efficacy of the Artificial Urinary Sphincter ZSI 375 for Treatment of Post-Radical Prostatectomy Incontinence in Patients with Intrinsic Sphincter Deficiency: A Preliminary Study". European Medical Journal. 2017-06-01. Retrieved 2022-07-22.