Y15 may refer to:
- Greek submarine Argonaftis (Y15) or HMS Virulent (P95), V-class submarine of the Royal Navy
- Y-15 Aix/Les Milles or Aix-en-Provence Aerodrome in the Bouches-du-Rhône department of the Provence-Alpes-Côte d'Azur region of France
- Youth Bandy World Championship World Championship Y15, for boys' teams up to age 15
- Y15, 1,2,4,5-benzenetetraamine tetrahydrochloride, an FAK inhibitor intended for cancer
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