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Wikipedia:USEP/Courses/JHU MolBio Ogg SP14/Group 82F

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GROUP PAGE

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Is this our group page??

Klbarnhill (talk) 20:40, 25 February 2014 (UTC)[reply]

Initial article assessments from SabFernMB

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Capping Enzyme

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[1] [2] [3]

  1. It does not comply with the manual of style guidelines for lead sections, layout, list incorporation, etc.
  2. It lacks reliable and adequate resources. It contains some references but in-line citations are missing. The references provided are not in accordance with the layout style of guideline.
  3. It provides very little meaningful content. For example, information on the structure is missing. More information will be required
  4. It does not contain images, illustrations, charts, etc. For example, add enzyme structure, illustration of how mRNA are capped.

5S ribosomal RNA

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[4] [5] [6] [7]

  1. It does not comply with the manual of style guidelines for lead sections, table of contents, layout, etc.
  2. It lacks reliable and adequate resources. Some in-line citations are missing.
  3. It provides some meaningful content, however more information is required e.g. location of activity
  4. A good start on the illustrations, but additional images would be helpful such as 5S ribosomal RNA interaction with other proteins.

References

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  1. ^ Neugebauer, KM (15 October 2002). "On the importance of being co-transcriptional". Journal of cell science. 115 (Pt 20): 3865–71. PMID 12244124.
  2. ^ Bentley, DL (June 2005). "Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors". Current opinion in cell biology. 17 (3): 251–6. PMID 15901493.
  3. ^ Cramer, P; Srebrow, A; Kadener, S; Werbajh, S; de la Mata, M; Melen, G; Nogués, G; Kornblihtt, AR (8 June 2001). "Coordination between transcription and pre-mRNA processing". FEBS Letters. 498 (2–3): 179–82. PMID 11412852.
  4. ^ Smirnov, AV; Entelis, NS; Krasheninnikov, IA; Martin, R; Tarassov, IA (December 2008). "Specific features of 5S rRNA structure - its interactions with macromolecules and possible functions". Biochemistry. Biokhimiia. 73 (13): 1418–37. PMID 19216709.
  5. ^ Barciszewska, MZ; Szymański, M; Erdmann, VA; Barciszewski, J (2001). "Structure and functions of 5S rRNA". Acta Biochimica Polonica. 48 (1): 191–8. PMID 11440169.
  6. ^ Szymański, M; Barciszewska, MZ; Erdmann, VA; Barciszewski, J (1 May 2003). "5 S rRNA: structure and interactions". The Biochemical journal. 371 (Pt 3): 641–51. PMID 12564956.
  7. ^ Gongadze, GM (December 2011). "5S rRNA and ribosome". Biochemistry. Biokhimiia. 76 (13): 1450–64. PMID 22339598.

Article Selection Rationale

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First, this article needs a lot of work, for it is just a Stub! Additionally, capping enzymes fall under the broad topic of Gene Expression, which is absolutely fascinating, for it governs everything! The talk page of the article indicates that this article falls within the scope of WikiProjects Genetics and WikiProject Molecular and Cellular Biology. This suggests the importance of capping enzymes, as indicated by the “Mid-importance” rating, at both the gene and cellular level. For example, the enzyme’s role in mRNA processing can impact downstream processes at the cellular level. As of now, the article is very short and not easily understandable to the average reader, and we even got a little overwhelmed by the terminology and the lack of adequate explanation. It is not a topic that we would claim to have mastered, so learning much more about this topic is an added bonus while contributing to the knowledge of others. We can do this by building upon what is currently written to provide a good overview, with illustrations, of the enzymes in regards to their structure, function and factors that impact their function, location of activity, just to name a few areas that can be covered in the article.

Klbarnhill (talk) 21:01, 4 March 2014 (UTC)[reply]

Unit 8 progress report

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  • A suggestion was made to remove the current content and replace with an update overview that is clearly referenced. No feedback was received to date on this suggestion
  • Let the original information, which will be later deleted if there are no objections to the removal
  • Added the preliminary outline to provide guidance on the structure of the article as well as to get feedback from other users on the outline
  • Updated lead section
  • Updated structure section

Unit 10 progress report

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  • Lead section and original data was combined to produce a general overview of the entire article
  • Function section was edited to include other mechanisms that depend on the cap
  • Wiki links were added to the lead, structure and see also sections
  • Formation of the cap section was added
  • An enzyme info box was added
  • Impact of the enzyme's activity section was added

Unit 12 progress report

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  • Addressed some of the reviewers comments
  • Addition of enzyme and 5'cap images
  • The Structure section was expanded to provided info on conserved sections of the enzyme
  • Additional references to the formation of the cap, structure and function sections were added
  • Additional wikilinks and categories under the "See also" section were added

Unit 14 progress report

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  • More wikilinks were added
  • Interaction between capping enzymes and RNA pol II explained
  • References cleaned up
  • Grammar errors corrected
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