VPI may refer to:
- Vapor phase infiltration, a synonym for sequential infiltration synthesis
- Velopharyngeal insufficiency, a medical term
- Verilog Procedural Interface, in computer programming
- Vertical Politics Institute, a conservative political action committee
- Vietnam Petroleum Institute
- Virginia Polytechnic Institute and State University (a.k.a. Virginia Tech)
- Virtual path identifier, in computer networking
- Visegrad Patent Institute, a patent organization created by the four Visegrad countries
- Vocational Preference Inventory
- VPI Industries, a manufacturer of phonographs
- VPIphotonics, photonic simulation tool
This disambiguation page lists articles associated with the title VPI.
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