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Basophil activation

JFW | T@lk 17:06, 24 July 2008 (UTC):It probably makes more sense for the content of basophil activation to be merged with basophil granulocyte.

men | T@lk 17:16, 24 July 2008 (UTC):i think merging basophil activation with basophil granulocyte is a good idea, but the complexity of the basophil activation (Iknow its not much yet, but i use wiki for about 3 hours :) deserves an own topic/site. The test method will be related to exactly that background and in the next years it will be become very popular, so i see a good article combinding the background and the test. There is no common name for this method yet, althougth it is performed more and more. what do you think ? can u plz answer on discussion page of the article ?

JFW | T@lk 17:51, 24 July 2008 (UTC):If the test is not being used today, I would not mention it in allergy. That would be premature.

men | T@lk 17:20, 24 July 2008 (UTC):you are totaly right. Its not used as an alternative yet, but the main idea works, as scientist want it to work.Its to early to dicribe the hole thing in your article, but u could link my article at the allergie test methods ...

Picture activation of article

men | T@lk 20:06, 24 July 2008 (UTC): can some one who is autoconfirmed or an administrator plz activate the picturelink to my article basophil activation

JFW | T@lk 20:27, 24 July 2008 (UTC): I can't find the image you are referring to. The upload log doesn't show any images uploaded from your account.

men | T@lk 20:31, 24 July 2008 (UTC): hmm... i uploaded it on wiki commons, and it actually worked (someone activated it i think), but then i accidently deleted the article, and now the pic permission is gone again. the filename is "Basophlie activation.JPG" iknow spelling is wrong :)

men | T@lk 20:41, 24 July 2008 (UTC): i uploaded it again

http://commons.wikimedia.org/wiki/Image:Basophile_activation.JPG

http://commons.wikimedia.org/wiki/Image:Basophil_activation.JPG

JFW | T@lk 20:46, 24 July 2008 (UTC): The filename is case-sensitive. When you change jpg to JPG the image displays OK.

men | T@lk 20:50, 24 July 2008 (UTC): Thanks for keeping cool with these newbies ;)

JFW | T@lk 21:10, 24 July 2008 (UTC): I have no difficulty with newbies who are fast learners, like yourself :-)

IgE and Fc receptor

Hi there Menue. My apologies for the delayed response - I was enjoying myself way too much on vacation. You were correct in your question - the high affinity Fcε receptor binds IgE with no bound antigen. When an antigen is present, it will crosslink the Fc receptors (in other words, bind to more than one IgE molecule attached to individual Fc receptors) to activate the cell (mast, basophil, eosinophil) and trigger degranulation. This is described in the Immunobiology textbook that is free online at NCBI. I'm not quite sure I follow the two figures that you linked on my talk-page - perhaps a caption would help? Is there a relevance to the FITC labeled antigen, for instance? Good to see a new editor on the immunology pages! Best wishes, ~ Ciar ~ _{(Talk to me!)} 08:07, 27 July 2008 (UTC)