1. subscript 2 in O2; superscript (+/-) in NADP+/FADH- 2. the first paragraph of the "mechanism" section should be broken into individual sentences 3. specific residues mentioned in the text should be labeled in the figure (e.g. tyrosine 201 and 222) 4. are there any structures that show the location of NADP relative to substrate? 5. "hydroxide" (HO-) is not being transferred--a formal "HO+" equivalent is. This should be clarified