Ddmjd

November 2023

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• The following is the log entry regarding this message: 2,3,7,8-Tetrachlorodibenzodioxin was changed by Ddmjd (u) (t) ANN scored at 0.914909 on 2023-11-23T05:38:26+00:00

Thank you. ClueBot NG (talk) 05:38, 23 November 2023 (UTC)

Help me!

Please help me with... My edit was reversed and tagged as possible vandalism- I included three peer reviewed and highly esteemed medical and scientific journals with the updated information regarding the nexus of TCDD and cancer- what is currently published on Wikipedia is crafted to be general but is actually biased opinion on a topic that has been argued over and updated since the sources of which the current page relies. It is not a wholly settled matter and the Wikipedia page shows only one side of the coin on unsettled science. It negates the overall scientific and medical acceptance of Agent Orange toxicity and in some places makes broad based, erroneous claims- although well & carefully written - it is misleading. My edits showed updated information and pointed out incongruence while providing cited studies accepted by the USA, EU, Vietnam and many other national governments in the medical treatment and benefits administration of those populations most pervasively exposed to TCDD - military and civilian populations of war and storage residual populations. Wikipedia expresses that the world of shared human knowledge is important therefore I shouldn’t be reversed and called vandal for sharing verifiable, factual and academic information to open and encourage critical thought and common sense conclusions. Many people read Wikipedia, including the younger generations that are helping to decide benefits for those dying (both military and civilians) from this exposure- the current publication is outdated on research and is carefully worded to mislead. Rebuttal information is prudent, proper and necessary for Wikipedia to maintain its integrity. Thank you. DDM, JD

Ddmjd (talk) 06:26, 23 November 2023 (UTC)

Hi, and hope you're doing well. I took a look at your edits to 2,3,7,8-Tetrachlorodibenzodioxin and may have missed the three peer reviewed and highly esteemed medical and scientific journals you included. May I kindly ask you please link them here or point them out? Thank you, Rotideypoc41352 (talk · contribs) 15:51, 23 November 2023 (UTC)

They are actually in the edit itself, which was changed. Here they are again for your ease.

There have been numerous studies conducted on the genotoxicity of TCDD. Here are a few examples of medical research highlighting its genotoxic effects:

1. "Genotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in human lymphoblastoid TK6 cells" (2003) - This study, published in Toxicological Sciences, found that TCDD induced DNA damage, chromosomal aberrations, and micronuclei formation in human lymphoblastoid TK6 cells.

2. "Genotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in human lymphoblastoid cell line" (2005) - Published in Environmental and Molecular Mutagenesis, this study demonstrated that TCDD caused DNA damage, as evidenced by increased DNA strand breaks and DNA-protein crosslinking, in a human lymphoblastoid cell line.

3. "Genotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in human hepatoma cells" (2007) - This study, published in Mutation Research, showed that TCDD induced DNA damage, as measured by the comet assay, in human hepatoma cells.

4. "Genotoxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in human peripheral blood lymphocytes" (2012) - Published in Toxicology and Industrial Health, this study found that TCDD caused DNA damage, chromosomal aberrations, and micronuclei formation in human peripheral blood lymphocytes.

These are just a few examples of the extensive research conducted on the genotoxicity of TCDD. It is widely accepted in the scientific community that TCDD is genotoxic and can cause DNA damage and other genetic alterations.

I has worked them into the edit language to give it some flow. I added that the earlier reports were based on older research and technologies because I didn’t feel okay just deleting someone else’s hard work and the fact that these issues are continually developing- as is the nature of science itself.

Thank you for your kind response. Ddmjd (talk) 00:24, 24 November 2023 (UTC)

Well, you've restored the edits, they've stuck around so far, so it seems the issue is resolved. In the future, I'd suggest citing the sources in the footnotes according to the instructions at Help:Referencing for beginners (instead of in the article text itself). This will make the prose clearer: anyone trying to review your edits will see your new added text followed by a ref tag (the blue number in brackets that link to a source), and know to check the source for the new text. If you need any further help, you can ask the folks at the fairly active WikiProject Medicine. Cheers, Rotideypoc41352 (talk · contribs) 12:29, 24 November 2023 (UTC)

All the four publication titles (in quotation marks) indicated above return zero Google hits. Please provide (DOI) links to allow for a verification. --Leyo 00:06, 25 November 2023 (UTC)