User talk:AlexGallon/Reagent testing

Reagent testing is the process of using one or more reagents to determine the various chemicals contained within a sample of a drug.[1] While less discriminatory than other forms of drug checking (such as mass spectrometry), reagent testing is a useful harm reduction practice due to its relatively low cost and ease of use.[2] Reagent testing is also suitable for use by law enforcement agents for preliminary identification of substances in the field.[3][4]

(Image of my own reagents?)

A short animation providing clear instructions on how to use a reagent testing kit

Limitations

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As a presumptive test, a single reagent test cannot provide detailed information on exactly what is in the sample in question. However, a reagent test can be used to rule out the presence of a particular substance,[5][6] which can still be useful. For instance:

  • If a substance sold as MDMA tests negative for MDMA, the prospective user knows not to trust the identity of the drug, and may therefore choose not to ingest it.
  • If a substance sold as LSD tests negative for NBOMe compounds (which are occasionally sold in place of LSD[7]), and if the test results also suggest that LSD is present, the prospective user may make the informed choice to assume that the drug is unadulterated and therefore choose to ingest it.

In the second case, the user is still exposed to a level of risk from undetected adulterants, but the risk is reduced: they have successfully ruled out the presence of one class of harmful substances in the sample.

Reagent testing does not allow the tester to determine the potency or purity of the drug being tested.[5][6] While pill scrapings, powders, tabs and most liquids can be tested directly,[8] "geltabs" (small pieces of gelatine with the drug mixed in) are harder to test because the gelatine can interfere with the results.[9][10] For some drugs, including LSD, it is possible to extract the drug from the gelatine before testing.[9]

Procedure

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The basic steps of a reagent test are as follows:[5][11]

  1. Prepare a small amount sample of the substance to be tested.
    For a pill, the sample is just a small scraping; for liquids and powders, the sample is a small amount of the drug as-is; for blotter paper, a small cutting is sufficient.
  2. Put a small amount of reagent on top of the sample.
  3. Observe the colour change, if there is one.

(etc.)

(Image of results of an RT that I've done?)

References

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  1. ^ "Reagent Tests UK – Test MDMA, Cocaine, Ket and others". Reagent Tests UK. Archived from the original on 2024-06-11. Retrieved 2024-06-12.
  2. ^ Harper, Lane; Powell, Jeff; Pijl, Em M. (2017-07-31). "An overview of forensic drug testing methods and their suitability for harm reduction point-of-care services". Harm Reduction Journal. p. 52. doi:10.1186/s12954-017-0179-5. PMC 5537996. PMID 28760153. Retrieved 2024-06-12.{{cite web}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
  3. ^ Philp, Morgan; Fu, Shanlin (January 2018). "A review of chemical 'spot' tests: A presumptive illicit drug identification technique". Drug Testing and Analysis. pp. 95–108. doi:10.1002/dta.2300. Retrieved 13 June 2024.
  4. ^ O’Neal, Carol L; Crouch, Dennis J; Fatah, Alim A (April 2000). "Validation of twelve chemical spot tests for the detection of drugs of abuse". Forensic Science International. pp. 189–201. doi:10.1016/s0379-0738(99)00235-2. Retrieved 13 June 2024.
  5. ^ a b c Nasir, Ace. "Drug Checking Kit Instructions". DanceSafe. Archived from the original on 2024-05-20. Retrieved 2024-06-12.
  6. ^ a b "Drug Testing". Bristol Drugs Project. Archived from the original on 2024-05-22. Retrieved 2024-06-12.
  7. ^ Lipow, Matthew; Kaleem, Syed; Espiridion, Eduardo (2022-03-30). "NBOMe Toxicity and Fatalities: A Review of the Literature". Transformative Medicine (T-Med). pp. 12–18. doi:10.54299/tmed/msot8578. Retrieved 2024-06-12.
  8. ^ "How to Test Your Drugs with Reagents" (PDF). DanceSafe. Archived from the original (PDF) on 11 June 2024. Retrieved 13 June 2024.
  9. ^ a b Jones, Guy (13 February 2021). "How to extract and test a gelatine LSD tab (geltabs) with reagents – Reagent Tests UK". www.reagent-tests.uk. Archived from the original on 13 June 2024. Retrieved 13 June 2024.
  10. ^ "LSD Testing Kit". DanceSafe. 2 August 2019. Archived from the original on 13 June 2024. Retrieved 13 June 2024.
  11. ^ "Instructions for Using Reagent Tests – Reagent Tests UK". Reagent Tests UK. Archived from the original on 11 May 2024. Retrieved 13 June 2024.