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Steven Marc Muskal | |
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| Born | November 16, 1966 Glenview, Illinois, U.S. |
| Alma mater | Colorado School of Mines (BS) University of California, Berkeley (PhD)[1] |
| Known for | Cheminformatics |
| Spouse | Kirsten Muskal |
| Children | 2 |
Steven Muskal (born 1966) is an American scientist.
Biography
editSteven Muskal obtained his B.S. (1988) in engineering chemistry with computer science from the Colorado School of Mines and his PhD in Chemistry in 1991 from the University of California, Berkeley. From 1988 to 1991 he was a research assistant to Kim Sung-Hou.
From 1991 to 1995, he served as an Applications Scientist, Senior Scientist, and Product Manager at MDL Information Systems. From 1995-2000, he served as the Director of Scientific IT (Research Computing)[2] and as a Unit Director at the Affymax Research Institute. From 2000-Present, he has operated in several different executive management roles within private startup companies including VP informatics and Chief Technology Officer at Libraria (2000-2003), Sertanty (2003-2005) [3], and Eidogen-Sertanty[4] (2005-Present).
References
edit- ^ Muskal, Steven (1991). Predicting features of protein structure with computer-simulated neural networks. University of California, Berkeley ProQuest Dissertations Publishing.Muskal, Steven M.; Kim, Sung-Hou (June 1992). "Predicting protein secondary structure content". Journal of Molecular Biology. 225 (3): 713–727. doi:10.1016/0022-2836(92)90396-2.Muskal, Steven M.; Holbrook, Stephen R.; Kim, Sung-Hou (1990). "Prediction of the disulfide-bonding state of cysteine in proteins". "Protein Engineering, Design and Selection". 3 (8): 667–672. doi:10.1093/protein/3.8.667.Holbrook, Stephen R.; Muskal, Steven M.; Kim, Sung-Hou (1990). "Predicting surface exposure of amino acids from protein sequence". "Protein Engineering, Design and Selection". 3 (8): 659–665. doi:10.1093/protein/3.8.659.
- ^ Wessel, Matthew D.; Jurs, Peter C.; Tolan, John W.; Muskal, Steven M. (1 July 1998). "Prediction of Human Intestinal Absorption of Drug Compounds from Molecular Structure". Journal of Chemical Information and Computer Sciences. 38 (4): 726–735. doi:10.1021/ci980029a.McGregor, Malcolm J.; Muskal, Steven M. (25 May 1999). "Pharmacophore Fingerprinting. 1. Application to QSAR and Focused Library Design". Journal of Chemical Information and Computer Sciences. 39 (3): 569–574. doi:10.1021/ci980159j.McGregor, Malcolm J.; Muskal, Steven M. (1 January 2000). "Pharmacophore Fingerprinting. 2. Application to Primary Library Design". Journal of Chemical Information and Computer Sciences. 40 (1): 117–125. doi:10.1021/ci990313h.
- ^ Muskal, Steven M.; Jha, Sanjiv Kumar; Kishore, M. Phani; Tyagi, Prashant (1 September 2003). "A Simple and Readily Integratable Approach to Toxicity Prediction". Journal of Chemical Information and Computer Sciences. 43 (5): 1673–1678. doi:10.1021/ci034080c.
- ^ Schürer, Stephan C.; Muskal, Steven M. (28 January 2013). "Kinome-wide Activity Modeling from Diverse Public High-Quality Data Sets". Journal of Chemical Information and Modeling. 53 (1): 27–38. doi:10.1021/ci300403k.Sharma, Rajan; Schürer, Stephan C.; Muskal, Steven M. (26 October 2016). "High quality, small molecule-activity datasets for kinase research". F1000Research. 5: 1366. doi:10.12688/f1000research.8950.3.
{{cite journal}}: CS1 maint: unflagged free DOI (link)Schürer, Stephan C.; Tyagi, Prashant; Muskal, Steven M. (1 March 2005). "Prospective Exploration of Synthetically Feasible, Medicinally Relevant Chemical Space". Journal of Chemical Information and Modeling. 45 (2): 239–248. doi:10.1021/ci0496853.Vidović, Dušica; Muskal, Steven M.; Schürer, Stephan C. (21 December 2012). "Novel Kinase Inhibitors by Reshuffling Ligand Functionalities Across the Human Kinome". Journal of Chemical Information and Modeling. 52 (12): 3107–3115. doi:10.1021/ci3003842.Muskal, Steven M.; Sliman, Joe; Kokai-Kun, John; Pimentel, Mark; Wacher, Vince; Gottlieb, Klaus (22 June 2016). "Lovastatin lactone may improve irritable bowel syndrome with constipation (IBS-C) by inhibiting enzymes in the archaeal methanogenesis pathway". F1000Research. 5: 606. doi:10.12688/f1000research.8406.3.{{cite journal}}: CS1 maint: unflagged free DOI (link)Patel, Priya; Patel, Hiteshi; Vekariya, Dhara; Joshi, Chinmayi; Patel, Pooja; Muskal, Steven; Kothari, Vijay (5 July 2019). "Sonic Stimulation and Low Power Microwave Radiation Can Modulate Bacterial Virulence Towards Caenorhabditis elegans". Anti-Infective Agents. 17 (2): 150–162. doi:10.2174/2211352516666181102150049.