- INFO: Beginning work on FTO... {April 10, 2008 4:03:49 PM PDT}
- AMBIGUITY: Did not locate an acceptable page to update. {April 10, 2008 4:06:09 PM PDT}
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{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Fatso
| HGNCid =
| Symbol = FTO
| AltSymbols =; KIAA1752; MGC5149
| OMIM =
| ECnumber =
| Homologene = 8053
| MGIid = 1347093
| GeneAtlas_image1 = PBB_GE_FTO_209702_at_tn.png
| GeneAtlas_image2 = PBB_GE_FTO_gnf1h06407_at_tn.png
| Function =
| Component =
| Process =
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 79068
| Hs_Ensembl = ENSG00000140718
| Hs_RefseqProtein = XP_051200
| Hs_RefseqmRNA = XM_051200
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 16
| Hs_GenLoc_start = 52295569
| Hs_GenLoc_end = 52705845
| Hs_Uniprot =
| Mm_EntrezGene = 26383
| Mm_Ensembl = ENSMUSG00000055932
| Mm_RefseqmRNA = NM_011936
| Mm_RefseqProtein = NP_036066
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 8
| Mm_GenLoc_start = 94203637
| Mm_GenLoc_end = 94558542
| Mm_Uniprot =
}}
}}
'''Fatso''', also known as '''FTO''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: FTO fatso| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79068| accessdate = }}</ref>
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{{PBB_Summary
| section_title =
| summary_text =
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Chu X, Erdman R, Susek M, ''et al.'' |title=Association of morbid obesity with FTO and INSIG2 allelic variants. |journal=Archives of surgery (Chicago, Ill. : 1960) |volume=143 |issue= 3 |pages= 235-40; discussion 241 |year= 2008 |pmid= 18347269 |doi= 10.1001/archsurg.2007.77 }}
*{{cite journal | author=Freathy RM, Timpson NJ, Lawlor DA, ''et al.'' |title=Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected, given its effect on BMI. |journal=Diabetes |volume= |issue= |pages= |year= |pmid= 18346983 |doi= 10.2337/db07-1466 }}
*{{cite journal | author=Al-Attar SA, Pollex RL, Ban MR, ''et al.'' |title=Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample. |journal=Cardiovascular diabetology |volume=7 |issue= |pages= 5 |year= |pmid= 18339204 |doi= 10.1186/1475-2840-7-5 }}
*{{cite journal | author=Lawlor DA, Timpson NJ, Harbord RM, ''et al.'' |title=Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable. |journal=PLoS Med. |volume=5 |issue= 3 |pages= e33 |year= |pmid= 18336062 |doi= 10.1371/journal.pmed.0050033 }}
*{{cite journal | author=Grant SF, Li M, Bradfield JP, ''et al.'' |title=Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP. |journal=PLoS ONE |volume=3 |issue= 3 |pages= e1746 |year= |pmid= 18335027 |doi= 10.1371/journal.pone.0001746 }}
*{{cite journal | author=Do R, Bailey SD, Desbiens K, ''et al.'' |title=Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study. |journal=Diabetes |volume=57 |issue= 4 |pages= 1147-50 |year= |pmid= 18316358 |doi= 10.2337/db07-1267 }}
*{{cite journal | author=López-Bermejo A, Petry CJ, Díaz M, ''et al.'' |title=The Association between the FTO Gene and Fat Mass in Humans Develops by the Postnatal Age of Two Weeks. |journal=J. Clin. Endocrinol. Metab. |volume=93 |issue= 4 |pages= 1501-5 |year= |pmid= 18252780 |doi= 10.1210/jc.2007-2343 }}
*{{cite journal | author=Hunt SC, Stone S, Xin Y, ''et al.'' |title=Association of the FTO Gene With BMI. |journal=Obesity (Silver Spring) |volume=16 |issue= 4 |pages= 902-4 |year= |pmid= 18239580 |doi= 10.1038/oby.2007.126 }}
*{{cite journal | author=Price RA, Li WD, Zhao H |title=FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs. |journal=BMC Med. Genet. |volume=9 |issue= |pages= 4 |year= 2008 |pmid= 18218107 |doi= 10.1186/1471-2350-9-4 }}
*{{cite journal | author=Hinney A, Nguyen TT, Scherag A, ''et al.'' |title=Genome Wide Association (GWA) Study for Early Onset Extreme Obesity Supports the Role of Fat Mass and Obesity Associated Gene (FTO) Variants. |journal=PLoS ONE |volume=2 |issue= 12 |pages= e1361 |year= |pmid= 18159244 |doi= 10.1371/journal.pone.0001361 }}
*{{cite journal | author=Peeters A, Beckers S, Verrijken A, ''et al.'' |title=Variants in the FTO gene are associated with common obesity in the Belgian population. |journal=Mol. Genet. Metab. |volume=93 |issue= 4 |pages= 481-4 |year= |pmid= 18055244 |doi= 10.1016/j.ymgme.2007.10.011 }}
*{{cite journal | author=Gerken T, Girard CA, Tung YC, ''et al.'' |title=The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. |journal=Science |volume=318 |issue= 5855 |pages= 1469-72 |year= 2007 |pmid= 17991826 |doi= 10.1126/science.1151710 }}
*{{cite journal | author=Li H, Wu Y, Loos RJ, ''et al.'' |title=Variants in the fat mass- and obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population. |journal=Diabetes |volume=57 |issue= 1 |pages= 264-8 |year= 2008 |pmid= 17959933 |doi= 10.2337/db07-1130 }}
*{{cite journal | author=Andreasen CH, Stender-Petersen KL, Mogensen MS, ''et al.'' |title=Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation. |journal=Diabetes |volume=57 |issue= 1 |pages= 95-101 |year= 2008 |pmid= 17942823 |doi= 10.2337/db07-0910 }}
*{{cite journal | author=Horikoshi M, Hara K, Ito C, ''et al.'' |title=Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population. |journal=Diabetologia |volume=50 |issue= 12 |pages= 2461-6 |year= 2008 |pmid= 17928989 |doi= 10.1007/s00125-007-0827-5 }}
*{{cite journal | author=Ohashi J, Naka I, Kimura R, ''et al.'' |title=FTO polymorphisms in oceanic populations. |journal=J. Hum. Genet. |volume=52 |issue= 12 |pages= 1031-5 |year= 2008 |pmid= 17928949 |doi= 10.1007/s10038-007-0198-2 }}
*{{cite journal | author=Tschritter O, Preissl H, Yokoyama Y, ''et al.'' |title=Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans. |journal=Diabetologia |volume=50 |issue= 12 |pages= 2602-3 |year= 2008 |pmid= 17917711 |doi= 10.1007/s00125-007-0839-1 }}
*{{cite journal | author=Pascoe L, Tura A, Patel SK, ''et al.'' |title=Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function. |journal=Diabetes |volume=56 |issue= 12 |pages= 3101-4 |year= 2007 |pmid= 17804762 |doi= 10.2337/db07-0634 }}
*{{cite journal | author=Scuteri A, Sanna S, Chen WM, ''et al.'' |title=Genome-Wide Association Scan Shows Genetic Variants in the FTO Gene Are Associated with Obesity-Related Traits. |journal=PLoS Genet. |volume=3 |issue= 7 |pages= e115 |year= |pmid= 17658951 |doi= 10.1371/journal.pgen.0030115 }}
*{{cite journal | author=Field SF, Howson JM, Walker NM, ''et al.'' |title=Analysis of the obesity gene FTO in 14,803 type 1 diabetes cases and controls. |journal=Diabetologia |volume=50 |issue= 10 |pages= 2218-20 |year= 2008 |pmid= 17657473 |doi= 10.1007/s00125-007-0767-0 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on LOC642658... {April 10, 2008 4:06:22 PM PDT}
- CREATE: Found no pages, creating new page. {April 10, 2008 4:06:31 PM PDT}
- CREATED: Created new protein page: LOC642658 {April 10, 2008 4:06:46 PM PDT}
end log.
