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Colony hybridization is the process analyzing a certain genetic sequence of DNA, RNA, Proteins, Antibodies, Enzymes,^[1] or bacteria colonies.^[2] Hybridization has high specificity which allows it to find a specific sequence, even when it is surrounded by similar sequences.^[1]

Process

A cell culture is grown until it has a minimum of 50 colonies.^[3]
A sample of the culture is transferred onto nylon^[3] or nitrocellulose^[1] sheet.

References

^ ^a ^b ^c Melanie Overstreet. "Colony Hybridization". Retrieved 2010-02-26.
^ Maier, Raina (2009). Environmental Microbiology. Academic Press. p. 248. ISBN 9780123705198.
^ ^a ^b "Colony Hybridization Protocol" (PDF). 1999. Retrieved 2010-02-26.

[vt.edu-1] Melanie Overstreet. "Colony Hybridization". Retrieved 2010-02-26.

[2] Maier, Raina (2009). Environmental Microbiology. Academic Press. p. 248. ISBN 9780123705198.

[ucdavis-3] "Colony Hybridization Protocol" (PDF). 1999. Retrieved 2010-02-26.

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