Synaptic Noise Project Proposal.
Group Members: Waleed Farag, Kevin Murtagh, Nina Verghis
Intro
edit- Definition of synaptic noise
- General overview
Implications of Synaptic Noise
edit- Seen as both a positive and negative occurrence
- Relation to stochastic noise
In the Hippocampus
edit- Significance to memories
- How it affects
- Injuries and implications of synaptic noise and diseases
In Sensory Neurons
edit- Overview of sensory neurons
- How synaptic noise affects and is needed
Division of Work
editThe group will work independently to collect and analyze sources. We will also meet at regularly scheduled times to compile our information and to form a clear and comprehensive article.
References
editCalvin, William H., and Charles F. Stevens. "Synaptic Noise and Other Sources of Randomness in Motoneuron Interspike Intervals." Journal of Neurophysiology (1968): 574-87. PubMed.gov. Web.
Demb, J. B. "How Retinal Ganglion Cells Prevent Synaptic Noise From Reaching the Spike Output." Journal of Neurophysiology 92.4 (2004): 2510-519. Web.
Destexhe, A., M. Badoual, Z. Piwkowska, T. Bal, and M. Rudolph. "A Novel Method for Characterizing Synaptic Noise in Cortical Neurons." Neurocomputing 58-60 (2004): 191-96. Web.
Dideriksen J. L., F. Negro, R. M. Enoka and D. Farina. "Motor unit recruitment strategies and muscle properties determine the influence of synaptic noise on force steadiness." Journal of Neurophysiology (2012):107:3357-3369. Web.
Kohn, A. F. "Effects of synaptic noise on a neuronal pool model with strong excitatory drive and recurrent inhibition." (1998) BioSystems, 48 (1-3), pp. 113-121. ScienceDirect.com. Web.
Medina, J.F., S.G. Lisberger. "Variation, signal, and noise in cerebellar sensory-motor processing for smooth-pursuit eye movements." Journal of Neuroscience. (2007):27:6832–6842.
Prescott, Steven A., and Yves De Koninck. "Gain Control of Firing Rate by Shunting Inhibition: Roles of Synaptic Noise and Dendritic Saturation." Proceedings of the National Academy of Sciences 100.4 (2003): 2076-081. Web.
Stein, R.B., Gossen, E.R. & Jones, K.E. "Neuronal variability: noise or part of the signal? Nat. Rev. Neurosci. (2005), 6, 389–397.
Wahl, L.M., J.J.B. Jack, A.U. Larkman, K.J. Stratford. "The effects of synaptic noise on measurements of evoked excitatory postsynaptic response amplitudes."(1997) Biophysical Journal, 73 (1), pp. 205-219. ScienceDirect.com. Web.