User:Mr. Ibrahem/Streptozotocin

Mr. Ibrahem/Streptozotocin
Clinical data
Trade names	Zanosar
AHFS/Drugs.com	Monograph
MedlinePlus	a684053
Routes of; administration	Intravenous
Drug class	Alkylating agent
Legal status
Legal status	In general: ℞ (Prescription only);
Pharmacokinetic data
Bioavailability	17–25% (100% if IV)
Metabolism	Liver, kidney
Elimination half-life	35–40 minutes
Identifiers
	IUPAC name 2-Deoxy-2-({[methyl(nitroso)amino]carbonyl}amino)-β-D-glucopyranose;
Chemical and physical data
Formula	C8H15N3O7
Molar mass	265.222 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO)O)O)N=O;
	InChI InChI=1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1 ; Key:ZSJLQEPLLKMAKR-GKHCUFPYSA-N ;
	(what is this?) (verify)

Streptozotocin, also known as streptozocin (STZ), is a medication used for treating certain islet cell cancer of the pancreas, carcinoid tumor, and pancreatic adenocarcinoma.^[1] It is given by injection into a vein.^[1]

Common side effects include nausea, kidney problems, and bone marrow suppression.^[1] Other side effects may include liver problems, confusion, and pain at the site of injection.^[1] Use during pregnancy may harm the baby.^[1] It is a alkylating agent.^[1]

Streptozotocin was approved for medical use in the United States in 1982.^[1] In the United Kingdom it cost the NHS about £570 per 1 gram as of 2021.^[2] This amount in the United States costs about 370 USD.^[3] It is sold under the brand name Zanosar among others.^[1]

References edit

^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k "Streptozocin Monograph for Professionals". Drugs.com. Archived from the original on 7 September 2015. Retrieved 14 October 2021.
^ BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 949. ISBN 978-0-85711-369-6.{{cite book}}: CS1 maint: date format (link)
^ "Zanosar Prices, Coupons & Patient Assistance Programs". Drugs.com. Retrieved 15 October 2021.

[AHFS2021-1] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k "Streptozocin Monograph for Professionals". Drugs.com. Archived from the original on 7 September 2015. Retrieved 14 October 2021.

[BNF80-2] BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 949. ISBN 978-0-85711-369-6.{{cite book}}: CS1 maint: date format (link)

[3] "Zanosar Prices, Coupons & Patient Assistance Programs". Drugs.com. Retrieved 15 October 2021.

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