Mr. Ibrahem/Sevelamer
Clinical data
Pronunciation(/sɛˈvɛləmər/ or /sɛˈvɛləmɪər/)
Trade namesRenagel, Renvela
AHFS/Drugs.comMonograph
MedlinePlusa601248
License data
Pregnancy
category
  • AU: B3
Routes of
administration
By mouth
Legal status
Legal status
  • AU: S4 (Prescription only)
  • US: ℞-only
  • EU: Rx only
Pharmacokinetic data
Bioavailability0%
ExcretionFeces 100%
Identifiers
  • poly(allylamine-
    co-N,N'-diallyl-1,3-diamino-2-hydroxypropane)
Chemical and physical data
Formula[(C3H7N)a+b.(C9H17N2O)c]m
where a+b:c = 9:1
Molar massvariable
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Sevelamer, sold under the brand name Renagel among others, is a medication used to treat hyperphosphatemia in chronic kidney disease.[1] In the United Kingdom it is a second line treatment.[2] It is taken by mouth with meals.[1]

Common side effects include abdominal pain, diarrhea, nausea, and constipation.[1] A skin rash may also occur.[2] It works by binding phosphate in the intestines.[1]

Sevelamer was approved for medical use in the United States in 1998.[1] In the United States it costs about 48 USD for 270 tablets of 800 mg as of 2021.[3] This amount in the United Kingdom costs the NHS about £75.[2]

References edit

  1. ^ a b c d e f g h "Sevelamer Monograph for Professionals". Drugs.com. Archived from the original on 30 November 2020. Retrieved 12 October 2021.
  2. ^ a b c BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 1116. ISBN 978-0-85711-369-6.{{cite book}}: CS1 maint: date format (link)
  3. ^ "Sevelamer Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 19 January 2021. Retrieved 7 April 2021.