Clinical data | |
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Trade names | Pyridium, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a682231 |
License data |
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Pregnancy category |
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Routes of administration | By mouth |
Drug class | Azo dye[1] |
Legal status | |
Legal status |
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Identifiers | |
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Chemical and physical data | |
Formula | C11H11N5 |
Molar mass | 213.244 g·mol−1 |
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Phenazopyridine, sold under the brand name Pyridium among others, is a medication used to help with the discomfort caused by urinary tract infection, surgery, or injury to the urinary tract.[1] For urinary tract infection it may be used together with antibiotics for the first two days.[1] It is taken by mouth.[1]
Side effects may include orange colored urine and other body fluids.[1][2] Other side effects may include yellowish skin, methemoglobinemia, sulfhemoglobinemia, and hemolytic anemia.[1][3] Use is not recommended in those with kidney or liver problems.[1] There is no evidence of harm with use during pregnancy.[4] Use during breastfeeding is not recommended.[4] Phenazopyridine is a azo dye and how it works is not entirely clear.[1]
Phenazopyridine came into medical use in the 1930s.[5] It maybe available as a generic medication and over the counter.[1][6] In the United States six doses of 200 mg costs about 8 USD as of 2020.[7] It is not easily available in Canada as of 2015, though some pharmacies will make it.[8]
References
edit- ^ a b c d e f g h i j k "Phenazopyridine Hydrochloride Monograph for Professionals". Drugs.com. Archived from the original on 25 July 2019. Retrieved 13 October 2020.
- ^ a b Moldwin, Robert M. (2017). Urological and Gynaecological Chronic Pelvic Pain: Current Therapies. Springer. p. 237. ISBN 978-3-319-48464-8. Archived from the original on 2021-08-28. Retrieved 2020-10-13.
- ^ "Phenazopyridine". Drugs and Lactation Database (LactMed). National Library of Medicine (US). October 31, 2018. Archived from the original on 26 February 2021. Retrieved 13 October 2020.
- ^ a b "Phenazopyridine Use During Pregnancy". Drugs.com. Archived from the original on 2021-01-24. Retrieved 2020-10-13.
- ^ Sneader, Walter (2005). Drug Discovery: A History. John Wiley & Sons. p. 383. ISBN 978-0-471-89979-2. Archived from the original on 2021-08-28. Retrieved 2020-10-13.
- ^ Wang, A; Nizran, P; Malone, MA; Riley, T (September 2013). "Urinary tract infections". Primary care. 40 (3): 687–706. doi:10.1016/j.pop.2013.06.005. PMID 23958364.
- ^ "Phenazopyridine Prices and Phenazopyridine Coupons". GoodRx. Archived from the original on 17 June 2019. Retrieved 13 October 2020.
- ^ "Calgary doctor answers 'burning' questions about bladder infections". CBC. Archived from the original on 29 August 2018. Retrieved 13 October 2020.