{{#unlinkedwikibase:id=Q416475}}
 Ball-and-stick model of the glutaraldehyde molecule | |
| Clinical data | |
|---|---|
| Other names | Glutaraldehyde Glutardialdehyde Glutaric acid dialdehyde Glutaric aldehyde Glutaric dialdehyde 1,5-Pentanedial |
| Identifiers | |
| Chemical and physical data | |
| Formula | C5H8O2 |
| Molar mass | 100.117 g·mol−1 |
| 3D model (JSmol) | |
| |
Glutaraldehyde, sold under the brandname Cidex and Glutaral among others, is a disinfectant, medication, preservative, and fixative.[3][4][6][7] As a disinfectant, it is used to sterilize surgical instruments and other areas of hospitals.[3] As a medication, it is used to treat warts on the bottom of the feet.[4] Glutaraldehyde is applied as a liquid.[3]
Side effects include skin irritation.[4] If exposed to large amounts, nausea, headache, and shortness of breath may occur.[3] Protective equipment is recommended when used, especially in high concentrations.[3] Glutaraldehyde is effective against a range of microorganisms including spores.[3][8] Glutaraldehyde is a dialdehyde.[9] It works by a number of mechanisms.[8]
Glutaraldehyde came into medical use in the 1960s.[10] It is on the World Health Organization's List of Essential Medicines.[11] The wholesale cost in the developing world is about US$1.50–7.40 per liter of 2% solution.[12] There are a number of other commercial uses such as leather tanning.[13]
References edit
- ^ Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 907. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.
- ^ "Glutaraldehyde". pubchem.ncbi.nlm.nih.gov. Archived from the original on 12 November 2020. Retrieved 19 December 2020.
- ^ a b c d e f g World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 323, 325. hdl:10665/44053. ISBN 9789241547659.
- ^ a b c d British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. p. 825. ISBN 9780857111562.
- ^ "WHOCC - ATC/DDD Index". www.whocc.no. Archived from the original on 1 July 2021. Retrieved 14 September 2020.
- ^ Bonewit-West, Kathy (2015). Clinical Procedures for Medical Assistants. Elsevier Health Sciences. p. 96. ISBN 9781455776610. Archived from the original on 2017-09-23. Retrieved 2017-09-09.
- ^ Sullivan, John Burke; Krieger, Gary R. (2001). Clinical Environmental Health and Toxic Exposures. Lippincott Williams & Wilkins. p. 601. ISBN 9780683080278. Archived from the original on 2019-02-23. Retrieved 2019-02-22.
- ^ a b Fraise, Adam P.; Maillard, Jean-Yves; Sattar, Syed (2012). Russell, Hugo and Ayliffe's Principles and Practice of Disinfection, Preservation and Sterilization. John Wiley & Sons. p. Chapter 2. ISBN 9781118425862. Archived from the original on 2017-09-23.
- ^ Pfafflin, James R.; Ziegler, Edward N. (2006). Encyclopedia of Environmental Science and Engineering: A-L. CRC Press. p. 235. ISBN 9780849398438. Archived from the original on 2020-08-01. Retrieved 2019-05-26.
- ^ Booth, Anne (1998). Sterilization of Medical Devices. CRC Press. p. 8. ISBN 9781574910872. Archived from the original on 2017-09-23.
- ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ "Glutaraldehyde". International Drug Price Indicator Guide. Archived from the original on 15 October 2018. Retrieved 8 December 2016.
- ^ Rietschel, Robert L.; Fowler, Joseph F.; Fisher, Alexander A. (2008). Fisher's Contact Dermatitis. PMPH-USA. p. 359. ISBN 9781550093780. Archived from the original on 2017-09-23.