Mr. Ibrahem/Frovatriptan
Clinical data
Trade namesFrova, Migard, others
Other namesFrovatriptan succinate, 6-methylamino-6,7,8,9-tetrahydro-5H-carbazole-3-carboxamide
(6R)-6-methylamino-6,7,8,9-tetrahydro-5H-carbazole-3-carboxamide
AHFS/Drugs.comMonograph
MedlinePlusa604013
Pregnancy
category
  • AU: B3
Routes of
administration
By mouth
Drug classTriptan[1]
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability20–30%
MetabolismLiver
Elimination half-life26 hours
ExcretionKidney
Identifiers
  • (+)-(R)-3-Methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole
Chemical and physical data
FormulaC14H17N3O
Molar mass243.310 g·mol−1
3D model (JSmol)
  • CN[C@@H]3CCc2[nH]c1ccc(C(N)=O)cc1c2C3
  • InChI=1S/C14H17N3O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18)/t9-/m1/s1 checkY
  • Key:XPSQPHWEGNHMSK-SECBINFHSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Frovatriptan, sold under the brand name Frova among others, is a medication used to treat migraine headaches.[1] It may also be used to prevent menstrual migraine.[2] It is taken by mouth.[2]

Common side effects include tiredness, numberness, flushing, dry mouth, pain, heart burn, and trouble sleeping.[1] Other side effects may include serotonin syndrome, high blood pressure, heart attack, and medication overuse headaches.[1] Safety in pregnancy is unclear, and use within 24 hours of breastfeeding is not recommended.[3] It is a triptan.[1]

was approved for medical use in the United States in 2001.[1] It is available as a generic medication. In the United Kingdom 6 pills of 2.5 mg costs the NHS about £6 as of 2021.[2] This amount in the United States costs about 67 USD.[4]

References edit

  1. ^ a b c d e f g h "Frovatriptan Monograph for Professionals". Drugs.com. Archived from the original on 26 January 2021. Retrieved 12 December 2021.
  2. ^ a b c d BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 500. ISBN 978-0857114105.
  3. ^ "Frovatriptan (Frova) Use During Pregnancy". Drugs.com. Archived from the original on 28 November 2020. Retrieved 12 December 2021.
  4. ^ "Frovatriptan Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 11 October 2016. Retrieved 12 December 2021.