Fibroadenoma
Other namesBreast mice, breast mouse[1]
Histopathologic image of breast fibroadenoma. Core needle biopsy. H&E stain.
SpecialtyGynecology
SymptomsRound, firm, and easy to move breast lump up to 3 cm[2][3]
Usual onset15 and 35 years[3]
TypesPericanalicular, intracanalicular[4]
CausesUnknown[1]
Risk factorsPregnancy, hormone replacement therapy[2]
Diagnostic methodExamination, ultrasound, mammography, needle biopsy[3][1]
Differential diagnosisBreast cancer, phyllodes tumors, lipoma, breast cyst, fat necrosis[3][1]
TreatmentNone, observation, removal by surgery or biopsy[3][1]
Frequency25% of women[3]

Fibroadenomas, also known as breast mice, are a type of non-serious breast tumour.[2] They often feel round, firm, and are easy to move within the breast.[2] They are typically up to 3 cm in size and are not painful.[2][3] In about 70% of cases they occur singularly.[1] They are not associated with breast cancer;[2] though may result in anxiety or unequal breast size.[1]

The cause is unknown.[1] They may become more noticeable during pregnancy or hormone replacement therapy and shrink following menopause.[2] They contain a mixture of connective and glandular tissue.[2] Diagnosis may be supported by examination, ultrasound, mammography, and needle biopsy.[3][1] It involves ruling out other types of breast lumps including breast cancer and phyllodes tumors.[3]

If there are no symptoms, no treatment beyond reassurance and follow-up is required.[3][1] In cases that are bothersome, removal by surgery or biopsy is an option.[3] Other techniques that are being looked at include cryoablation and high-intensity focused ultrasound (HIFU).[3] Fibroadenomas affect about 25% of women.[3] They most often begin between the age of 15 and 35 years.[3] The name breast mice refers to their high mobility within the breast.[1]

References edit

  1. ^ a b c d e f g h i j k Salati, SA (7 December 2020). "Breast fibroadenomas: a review in the light of current literature". Polski przeglad chirurgiczny. 93 (1): 40–48. doi:10.5604/01.3001.0014.5676. PMID 33729177.
  2. ^ a b c d e f g h "Breast Health: Follow-up after an abnormal mammogram - NCI". www.cancer.gov. 30 October 2014. Archived from the original on 5 September 2023. Retrieved 19 October 2023.
  3. ^ a b c d e f g h i j k l m n Stachs, A; Stubert, J; Reimer, T; Hartmann, S (9 August 2019). "Benign Breast Disease in Women". Deutsches Arzteblatt international. 116 (33–34): 565–574. doi:10.3238/arztebl.2019.0565. PMID 31554551.
  4. ^ Oprić, S; Oprić, D; Gugić, D; Granić, M (March 2012). "Phyllodes tumors and fibroadenoma common beginning and different ending". Collegium antropologicum. 36 (1): 235–41. PMID 22816226.