Mr. Ibrahem/Felbamate
Clinical data
Trade namesFelbatol
AHFS/Drugs.comMonograph
MedlinePlusa606011
Routes of
administration
By mouth (tablets, suspension)
Drug classAnticonvulsant
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability>90%
MetabolismLiver
Elimination half-life20–23 hours
Identifiers
  • (3-carbamoyloxy-2-phenylpropyl) carbamate
Chemical and physical data
FormulaC11H14N2O4
Molar mass238.24 g·mol−1
3D model (JSmol)
  • O=C(N)OCC(c1ccccc1)COC(N)=O
  • InChI=1S/C11H14N2O4/c12-10(14)16-6-9(7-17-11(13)15)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H2,12,14)(H2,13,15) checkY
  • Key:WKGXYQFOCVYPAC-UHFFFAOYSA-N checkY
  (verify)

Felbamate, sold under the brand name Felbatol, is medication used to treat epilepsy.[1] It is specifically used to treat partial seizures and Lennox–Gastaut syndrome.[1] It is only recommended with safer options are not effective.[1] It is taken by mouth.[1]

Common side effects include loss of appetite, nausea, trouble sleeping, and headache.[1] Side effects may include aplastic anemia, liver failure, Stevens-Johnson syndrome, and suicide.[1] Safety in pregnancy is unclear.[1] How it works is not clear.[1]

Felbamate was approved for medical use in the United States in 1993.[1] It is not approved in the United Kingdom, but can be acquired if other option are not effective.[2] In the United States 30 tablets of 600 mg cost about 95 USD as of 2021.[3]

References edit

  1. ^ a b c d e f g h i j k "Felbamate Monograph for Professionals". Drugs.com. Archived from the original on 6 November 2021. Retrieved 10 December 2021.
  2. ^ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 324. ISBN 978-0857114105.
  3. ^ "Felbamate Prices, Coupons & Patient Assistance Programs". Drugs.com. Retrieved 10 December 2021.