Encephalitis | |
---|---|
MRI scan image shows high signal in the temporal lobes and right inferior frontal gyrus in someone with HSV encephalitis. | |
Specialty | Neurology, infectious disease |
Symptoms | Headache, fever, confusion, stiff neck, vomiting[1] |
Complications | Seizures, trouble speaking, memory problems, problems hearing[1] |
Duration | Weeks to months for recovery[1] |
Types | Herpes simplex, West Nile, rabies, Eastern equine, others[2] |
Causes | Infection, autoimmune, certain medication, unknown[2] |
Diagnostic method | Based on symptoms, supported by blood tests, medical imaging, analysis of cerebrospinal fluid[2] |
Treatment | Antiviral medication, anticonvulsants, corticosteroids, artificial respiration[1] |
Prognosis | Variable[1] |
Frequency | 4.3 million (2015)[3] |
Deaths | 150,000 (2015)[4] |
Encephalitis is inflammation of the brain.[5] The severity can be variable with symptoms including headache, fever, confusion, a stiff neck, and vomiting.[1] Complications may include seizures, hallucinations, trouble speaking, memory problems, and problems with hearing.[1]
Causes of encephalitis include viruses such as herpes simplex virus and rabies as well as bacteria, fungi, or parasites.[1][2] Other causes include autoimmune diseases and certain medications.[2] In many cases the cause remains unknown.[2] Risk factors include a weak immune system.[2] Diagnosis is typically based on symptoms and supported by blood tests, medical imaging, and analysis of cerebrospinal fluid.[2]
Certain types are preventable with vaccines.[5] Treatment may include antiviral medications (such as acyclovir), anticonvulsants, and corticosteroids.[1] Treatment generally takes place in hospital.[1] Some people require artificial respiration.[1] Once the immediate problem is under control, rehabilitation may be required.[2] In 2015, encephalitis was estimated to have affected 4.3 million people and resulted in 150,000 deaths worldwide.[3][4]
References edit
- ^ a b c d e f g h i j k "Meningitis and Encephalitis Information Page". NINDS. Archived from the original on 29 October 2017. Retrieved 29 October 2017.
- ^ a b c d e f g h i "Meningitis and Encephalitis Fact Sheet". National Institute of Neurological Disorders and Stroke. Archived from the original on 29 October 2017. Retrieved 29 October 2017.
- ^ a b GBD 2015 Disease and Injury Incidence and Prevalence Collaborators (8 October 2016). "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282.
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has generic name (help)CS1 maint: numeric names: authors list (link) - ^ a b GBD 2015 Mortality and Causes of Death Collaborators (8 October 2016). "Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1459–1544. doi:10.1016/S0140-6736(16)31012-1. PMC 5388903. PMID 27733281.
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has generic name (help)CS1 maint: numeric names: authors list (link) - ^ a b "Encephalitis". NHS Choices. 2016. Archived from the original on 22 September 2017. Retrieved 29 October 2017.