Encephalitis
MRI scan image shows high signal in the temporal lobes and right inferior frontal gyrus in someone with HSV encephalitis.
SpecialtyNeurology, infectious disease
SymptomsHeadache, fever, confusion, stiff neck, vomiting[1]
ComplicationsSeizures, trouble speaking, memory problems, problems hearing[1]
DurationWeeks to months for recovery[1]
TypesHerpes simplex, West Nile, rabies, Eastern equine, others[2]
CausesInfection, autoimmune, certain medication, unknown[2]
Diagnostic methodBased on symptoms, supported by blood tests, medical imaging, analysis of cerebrospinal fluid[2]
TreatmentAntiviral medication, anticonvulsants, corticosteroids, artificial respiration[1]
PrognosisVariable[1]
Frequency4.3 million (2015)[3]
Deaths150,000 (2015)[4]

Encephalitis is inflammation of the brain.[5] The severity can be variable with symptoms including headache, fever, confusion, a stiff neck, and vomiting.[1] Complications may include seizures, hallucinations, trouble speaking, memory problems, and problems with hearing.[1]

Causes of encephalitis include viruses such as herpes simplex virus and rabies as well as bacteria, fungi, or parasites.[1][2] Other causes include autoimmune diseases and certain medications.[2] In many cases the cause remains unknown.[2] Risk factors include a weak immune system.[2] Diagnosis is typically based on symptoms and supported by blood tests, medical imaging, and analysis of cerebrospinal fluid.[2]

Certain types are preventable with vaccines.[5] Treatment may include antiviral medications (such as acyclovir), anticonvulsants, and corticosteroids.[1] Treatment generally takes place in hospital.[1] Some people require artificial respiration.[1] Once the immediate problem is under control, rehabilitation may be required.[2] In 2015, encephalitis was estimated to have affected 4.3 million people and resulted in 150,000 deaths worldwide.[3][4]

References edit

  1. ^ a b c d e f g h i j k "Meningitis and Encephalitis Information Page". NINDS. Archived from the original on 29 October 2017. Retrieved 29 October 2017.
  2. ^ a b c d e f g h i "Meningitis and Encephalitis Fact Sheet". National Institute of Neurological Disorders and Stroke. Archived from the original on 29 October 2017. Retrieved 29 October 2017.
  3. ^ a b GBD 2015 Disease and Injury Incidence and Prevalence Collaborators (8 October 2016). "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282. {{cite journal}}: |author= has generic name (help)CS1 maint: numeric names: authors list (link)
  4. ^ a b GBD 2015 Mortality and Causes of Death Collaborators (8 October 2016). "Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1459–1544. doi:10.1016/S0140-6736(16)31012-1. PMC 5388903. PMID 27733281. {{cite journal}}: |author= has generic name (help)CS1 maint: numeric names: authors list (link)
  5. ^ a b "Encephalitis". NHS Choices. 2016. Archived from the original on 22 September 2017. Retrieved 29 October 2017.