User:Mr. Ibrahem/Cefotetan

Mr. Ibrahem/Cefotetan
Clinical data
Trade names	Apatef, Cefotan, others
Other names	Cephotetan
AHFS/Drugs.com	Monograph
Routes of; administration	Injection
Drug class	Cephamycin
Legal status
Legal status	US: ℞-only;
Identifiers
	IUPAC name (7S)-7-{[4-(1-amino-3-hydroxy-1,3-dioxopropan-2-ylidene); 1,3-dithietane-2-carbonyl]amino}-7-methoxy-; 3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-; 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;
Chemical and physical data
Formula	C17H17N7O8S4
Molar mass	575.60 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C2N1/C(=C(\CS[C@@H]1[C@]2(OC)NC(=O)C3S/C(S3)=C(/C(=O)N)C(=O)O)CSc4nnnn4C)C(=O)O;
	InChI InChI=1S/C17H17N7O8S4/c1-23-16(20-21-22-23)34-4-5-3-33-15-17(32-2,14(31)24(15)7(5)11(29)30)19-9(26)13-35-12(36-13)6(8(18)25)10(27)28/h13,15H,3-4H2,1-2H3,(H2,18,25)(H,19,26)(H,27,28)(H,29,30)/b12-6-/t13?,15-,17+/m1/s1 ; Key:SRZNHPXWXCNNDU-IXOPCIAXSA-N ;
	(what is this?) (verify)

Cefotetan, sold under the brand name Cefotan among others, is an antibiotic used to treat bacterial infections.^[1] This includes joint infections, pelvic inflammatory disease, intra abdominal infections, pneumonia, and skin infections.^[1] It may also be used to prevent infection in people undergoing surgery.^[2] It is given by injection into a vein or muscle.^[1]

Common side effects include liver problems, allergic reactions, pain at the site of injection, and low platelets.^[1] Other side effects may include Clostridioides difficile infection and red blood cell breakdown.^[1] Safety in pregnancy is unclear.^[2] It is of the cephamycin and β-lactam class.^[1] It may be grouped with second-generation cephalosporins.^[1]

Cefotetan was approved for medical use in the United States in 1985.^[1] It is available as a generic medication.^[1] In the United States 10 doses of 2 grams costs about 400 USD as of 2021.^[3]

References

^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l "CefoTEtan Monograph for Professionals". Drugs.com. Archived from the original on 26 January 2021. Retrieved 30 December 2021.
^ ^a ^b "DailyMed - cefotan- cefotetan disodium injection, solution cefotan- cefotetan disodium injection, powder, for solution". dailymed.nlm.nih.gov. Archived from the original on 28 December 2021. Retrieved 30 December 2021.
^ "Cefotetan Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 17 January 2021. Retrieved 30 December 2021.

[AHFS2021-1] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l "CefoTEtan Monograph for Professionals". Drugs.com. Archived from the original on 26 January 2021. Retrieved 30 December 2021.

[PI2021-2] "DailyMed - cefotan- cefotetan disodium injection, solution cefotan- cefotetan disodium injection, powder, for solution". dailymed.nlm.nih.gov. Archived from the original on 28 December 2021. Retrieved 30 December 2021.

[3] "Cefotetan Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 17 January 2021. Retrieved 30 December 2021.

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