User:Latoya.thompson/sandbox

Mechanism of Action:

Diloxanide furoate destroys trophozoites of E. Histolica and prevents ameobic cyst formation. The exact mechanism of diloxanide is unknown; however, it is structurally related to chloramphenicol and may act in a similar way by blocking protein synthesis.^[1]

Indication:

Diloxanide is indicated as a monotherpay for Asymptomatic Ameobasis. It can be used to treat mild symptomatic amoebasis when combined with a 5-nitroimidazole such as metronidazole or tinidazole.^[2]

Contraindications:

Diloxanide furoate is contraindicated in pregnant women, women who are breast feeding, and in children <2 years of age.^[1]

^ ^a ^b Grayson, Lindsey (2010). Kucer's The Use of Antibiotics 6th Edition: A clinical Review of Antibacterial, Antifungal and Antiviral Drugs. 6000 Broken Sound Parkway, NW Suite 300 Boca Raton, FL 33487: CRC Press. p. 2121. ISBN 978-1-4441-4752-0.{{cite book}}: CS1 maint: location (link)
^ Arcangelo, Virginia Poole (2006). Pharmacotherapeutics For Advanced Practice: A Practical Approach. Lippincott Williams and Wilkins. p. 441. ISBN 978-0-7817-5784-3.

[:0-1] Grayson, Lindsey (2010). Kucer's The Use of Antibiotics 6th Edition: A clinical Review of Antibacterial, Antifungal and Antiviral Drugs. 6000 Broken Sound Parkway, NW Suite 300 Boca Raton, FL 33487: CRC Press. p. 2121. ISBN 978-1-4441-4752-0.{{cite book}}: CS1 maint: location (link)

[2] Arcangelo, Virginia Poole (2006). Pharmacotherapeutics For Advanced Practice: A Practical Approach. Lippincott Williams and Wilkins. p. 441. ISBN 978-0-7817-5784-3.

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