Starting a user page.
A bit about me edit
I'm User: Figgep In real life I go by as Fredrik. I am a Swedish pathologist and just this year (2017) started to edit and add knowledge-based text here. If you are the private type you can reach me through email.
Fredrik Ponten, MD, PhD with a professorship in surgical pathology at Uppsala University. I am a faculty member of the Department of Immunology, Genetics and Pathology and I have a clinical affiliation at the Clinical Department of Pathology, Uppsala University Hospital.
I am Clinical Director and co-founder of the Human Protein Atlas project. I have spent the last 15 years working on this non-commercial and academic project that is supported by a non-profit organization. Over 1200 man years have been spent on this project and all our scientific data and interpretations of results are made publically available without any restrictions at our web portal: www.proteinatlas.org.[1][2][3][4][5][6][7]
My main interest is in tissues and the molecular landscape that underlies phenotypic expression in both normal and diseased tissues, especially cancer tissue. I believe that the basic results presented at the Human Protein Atlas should be of common interest and as such provide an important complement to relevant pages on Wikipedia.
The summarized knowledge, with relevant links for deeper information, regarding the gene expression landscape in our normal organs and tissues provides the fundament for what makes a certain tissue type just that tissue type. It is the differences in global gene expression patterns that underlie the differences in anatomic appearance, histological composition and cellular functions, between different organs and tissue types in our bodies.
COI edit
While I am entirely a volunteer here I am adding details about the research I do and about the projects that I participate in. I do not accept money or honorariums for any efforts related to wikis, Wikipedia or the Internet. I do not and have not accepted any money from the Wikimedia Foundation or associated chapters.
References edit
- ^ Uhlén, Mathias; Fagerberg, Linn; Hallström, Björn M.; Lindskog, Cecilia; Oksvold, Per; Mardinoglu, Adil; Sivertsson, Åsa; Kampf, Caroline; Sjöstedt, Evelina (2015-01-23). "Tissue-based map of the human proteome". Science. 347 (6220): 1260419. doi:10.1126/science.1260419. ISSN 0036-8075. PMID 25613900.
- ^ Thul, Peter J.; Åkesson, Lovisa; Wiking, Mikaela; Mahdessian, Diana; Geladaki, Aikaterini; Blal, Hammou Ait; Alm, Tove; Asplund, Anna; Björk, Lars (2017-05-26). "A subcellular map of the human proteome". Science. 356 (6340): eaal3321. doi:10.1126/science.aal3321. ISSN 0036-8075. PMID 28495876.
- ^ Uhlen, Mathias; Zhang, Cheng; Lee, Sunjae; Sjöstedt, Evelina; Fagerberg, Linn; Bidkhori, Gholamreza; Benfeitas, Rui; Arif, Muhammad; Liu, Zhengtao (2017-08-18). "A pathology atlas of the human cancer transcriptome". Science. 357 (6352): eaan2507. doi:10.1126/science.aan2507. ISSN 0036-8075. PMID 28818916.
- ^ Uhlen, Mathias; Oksvold, Per; Fagerberg, Linn; Lundberg, Emma; Jonasson, Kalle; Forsberg, Mattias; Zwahlen, Martin; Kampf, Caroline; Wester, Kenneth. "Towards a knowledge-based Human Protein Atlas". Nature Biotechnology. 28 (12): 1248–1250. doi:10.1038/nbt1210-1248.
- ^ Pontén, Fredrik; Gry, Marcus; Fagerberg, Linn; Lundberg, Emma; Asplund, Anna; Berglund, Lisa; Oksvold, Per; Björling, Erik; Hober, Sophia (2009-01-01). "A global view of protein expression in human cells, tissues, and organs". Molecular Systems Biology. 5 (1): 337. doi:10.1038/msb.2009.93. ISSN 1744-4292. PMID 20029370.
- ^ Uhlen, Mathias; Ponten, Fredrik (2005-04-01). "Antibody-based Proteomics for Human Tissue Profiling". Molecular & Cellular Proteomics. 4 (4): 384–393. doi:10.1074/mcp.r500009-mcp200. ISSN 1535-9476. PMID 15695805.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ Uhlén, Mathias; Björling, Erik; Agaton, Charlotta; Szigyarto, Cristina Al-Khalili; Amini, Bahram; Andersen, Elisabet; Andersson, Ann-Catrin; Angelidou, Pia; Asplund, Anna (2005-12-01). "A Human Protein Atlas for Normal and Cancer Tissues Based on Antibody Proteomics". Molecular & Cellular Proteomics. 4 (12): 1920–1932. doi:10.1074/mcp.m500279-mcp200. ISSN 1535-9476. PMID 16127175.
{{cite journal}}: CS1 maint: unflagged free DOI (link)