he Secretary of State still retains a few domestic responsibilities, such as being the keeper of the Great Seal and being the officer to whom a President or Vice-President of the United States wishing to resign must deliver an instrument in writing declaring the decision to resign.

On September 29, 1789, President Washington appointed Thomas Jefferson of Virginia, then Minister to France, to be the first United States Secretary of State. John Jay had been serving in as Secretary of Foreign Affairs as a holdover from the Confederation since before Washington had taken office and would continue in that capacity until Jefferson would return from Europe many months later.

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