User:Chrisereae/Murine Cytomegalovirus

This is not a Wikipedia article: It is an individual user's work-in-progress page, and may be incomplete and/or unreliable. For guidance on developing this draft, see Wikipedia:So you made a userspace draft.

Find sources: Google (books · news · scholar · free images · WP refs) · FENS · JSTOR · TWL
Easy tools: Citation bot (help) | Advanced: Fix bare URLs
This page was last edited by Timrollpickering (talk | contribs) 5 years ago. (Update timer)

Finished writing a draft article? Are you ready to request an experienced editor review it for possible inclusion in Wikipedia? Submit your draft for review!

Murine Cytomegalovirus(MCMV, Murid Herpesvirus 1, MuHV1) is a virus of Herpesviridae family which infects the common house mouse, Mus musculus. MCMV is a species of the genus Muromegalovirus within the family Betaherpesvirinae

Taxonomy

Murine Cytomegalovirus and Rat Cytomegalovirus are to date the only classified members of the Muromegalovirus within the Betaherpesvirinae.

Biology

Model for Cytomegalovirus Infection

Cytomegaloviruses exhibit strict host-species specificiy, and no animal model currently exists for Human Cytomegalovirus (HCMV, HHV-5). Because of this, in vivo studies of Cytomegalovirus infection are carried out using either Murine Cytomegalovirus, Rat Cytomegalovirus (Murid Herpesvirus 2) or Guinea Pig Cytomegalovirus; MCMV is the most commonly used model. Though the genomes of MCMV and Human Cytomegalovirus HCMV are colinear, only 78 of MCMV's >170 predicted open reading frames are conserved in HCMV, 40 of which are conserved among all mammalian and avian herpesviruses. ^[1]

References

^ 1

Fields Virology, 5th Edition. Chapter 69 "Cytomegaloviruses"

External links

[1] 1

[1]