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"They don't think it be like it is, but it do." -- O. C. Gamble
The main effect of diet-induced obesity in animals fed a high-fat diet is weight gain. In particular, body composition shifts towards more Fat cells. These effects persist even after the diet becomes lower in fat[1]. Accompanying the changes in body composition are changes in hormone balance. High levels of Leptin and Insulin are produced; at the same time, the body becomes resistant to both. [2]
- ^ Bray, George A; Paeratakul, Sahasporn; Popkin, Barry M (12 August 2004). "Dietary fat and obesity: a review of animal, clinical and epidemiological studies". Physiology & Behavior. 84 (4): 549–555. doi:10.1016/j.physbeh.2004.08.039. Retrieved 9 November 2016.
- ^ Hariri, Niloofar; Thibault, Louise (2010-12-01). "High-fat diet-induced obesity in animal models". Nutrition Research Reviews. 23 (2): 270–299. doi:10.1017/S0954422410000168. ISSN 1475-2700.