- List of Baltimore Orioles Opening Day starting pitchers 1901
- List of Boston Red Sox Opening Day starting pitchers 1901
- List of New York Yankees Opening Day starting pitchers 1901
- List of Tampa Bay Rays Opening Day starting pitchers 1998
- List of Toronto Blue Jays Opening Day starting pitchers 1977
- List of Chicago White Sox Opening Day starting pitchers 1901
- List of Cleveland Indians Opening Day starting pitchers 1901
- List of Detroit Tigers Opening Day starting pitchers 1901
- List of Kansas City Royals Opening Day starting pitchers 1969
- List of Minnesota Twins Opening Day starting pitchers 1901
- List of Los Angeles Angels of Anaheim Opening Day starting pitchers 1961
- List of Oakland Athletics Opening Day starting pitchers 1901
- List of Seattle Mariners Opening Day starting pitchers 1977
- List of Texas Rangers Opening Day starting pitchers 1961
National League
- List of Atlanta Braves Opening Day starting pitchers 1871
- List of Florida Marlins Opening Day starting pitchers 1993
- List of New York Mets Opening Day starting pitchers 1962
- List of Philadelphia Phillies Opening Day starting pitchers 1883
- List of Washington Nationals Opening Day starting pitchers 1969
- List of Chicago Cubs Opening Day starting pitchers 1871
- List of Cincinnati Reds Opening Day starting pitchers 1882
- List of Houston Astros Opening Day starting pitchers 1962
- List of Milwaukee Brewers Opening Day starting pitchers 1969
- List of Pittsburgh Pirates Opening Day starting pitchers 1882
- List of St. Louis Cardinals Opening Day starting pitchers 1882
- List of Arizona Diamondbacks Opening Day starting pitchers 1998
- List of Colorado Rockies Opening Day starting pitchers 1993
- List of Los Angeles Dodgers Opening Day starting pitchers 1883
- List of San Diego Padres Opening Day starting pitchers 1969
- List of San Francisco Giants Opening Day starting pitchers 1883