Colcemid-
The article on colcemid illustrates how it works but does not go into detail as to all the applications of the drug. It does touch on the specifics of attachment, or detachment of microtubules and how important the concentrations of the drug are to the cell in question. It may be possible to get more detailed in the mechanism. And are there specific ranges of colcemid for humans compared to other species?
There are no real examples of the drug working. For example, chromosomal loss due to colcemid effecting the movement of chromosomes during cell division. Some of the english is off as well in the article. Only a few minor changes to fix that.
![]() | This is a user sandbox of Akunz001. A user sandbox is a subpage of the user's user page. It serves as a testing spot and page development space for the user and is not an encyclopedia article. |
You identified some missing points so the next step? Find some citations and add more about the applications, It's not just a drug to treat people it is mostly used in research. A section on its use in research along with concentrations use in experiments and maybe links to various protocols or papers where it is used might be a huge contribution to this page. There is also obvious missing information on the drug structure, official names and numbers, etc. Look at another finished drug page and put the box on the top right corner like those. There is actually a lot that can be done with this one. Finally see if you can drop a link to your sandbox in the original page so that you can get feedback. Jparcoeur (talk) 13:53, 30 October 2015 (UTC)
WIKI EDIT
Uses————————————————————————————————————————————————————————————————————————————————Colcemid is used primarily for scientific reasearch in cells. It is used in a variety of ways, however until recently, was mostly used for the study of mitosis (Link to page) in cells. For example, microtubules are necessary for the splitting of cells. More importantly, the splitting and movement of chromosomes during the M phase (Link to page). Colcemid inhibition of microtubules causes aneuploidy (link to page) in mitotic cells where the microtubules fall apart before they can complete their function of pulling chromosomes into the daughter cell, or non- dysjunction of chromosomes (CITE 2).