Upu or UPU may refer to:
- Upu or Apu, a historical region surrounding Damascus
- Motusa, a group of villages in Fiji, one of which is Upu
- Unpentunium, a hypothetical chemical element with abbreviation Upu
- Universal Postal Union, a United Nations agency with acronym UPU
This disambiguation page lists articles associated with the title Upu.
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