Up in Mabel's Room may refer to:
- Up in Mabel's Room (play), a 1919 play written by Wilson Collison and Otto Harbach
- Up in Mabel's Room (1926 film), a 1926 silent film based on the play starring Marie Prevost
- Up in Mabel's Room (1944 film), a 1944 film remake of the 1926 film starring Marjorie Reynolds
- "Up in Mabel's Room", a song by the Everly Brothers from their 1971 album Stories We Could Tell
This disambiguation page lists articles associated with the title Up in Mabel's Room.
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