UTP—xylose-1-phosphate uridylyltransferase

In enzymology, an UTP—xylose-1-phosphate uridylyltransferase (EC 2.7.7.11) is an enzyme that catalyzes the chemical reaction

UTP:xylose-1-phosphate uridylyltransferase
Identifiers
EC no.2.7.7.11
CAS no.9026-20-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
UTP + alpha-D-xylose 1-phosphate diphosphate + UDP-xylose

Thus, the two substrates of this enzyme are UTP and alpha-D-xylose 1-phosphate, whereas its two products are diphosphate and UDP-xylose.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is UTP:alpha-D-xylose-1-phosphate uridylyltransferase. Other names in common use include xylose-1-phosphate uridylyltransferase, uridylyltransferase, xylose 1-phosphate, UDP-xylose pyrophosphorylase, uridine diphosphoxylose pyrophosphorylase, and xylose 1-phosphate uridylyltransferase. This enzyme participates in nucleotide sugars metabolism.

References

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  • Ginsburg V, Neufeld EF, Hassid WZ (1956). "Enzymatic Synthesis of Uridine Diphosphate Xylose and Uridine Diphosphate Arabinose". Proc. Natl. Acad. Sci. U.S.A. 42 (6): 333–5. Bibcode:1956PNAS...42..333G. doi:10.1073/pnas.42.6.333. PMC 528284. PMID 16578456.