USS Mackinac has been the name of more than one United States Navy ship, and may refer to:
- USS Mackinac (1917), a patrol boat in commission from 1917 to 1919
- USS Mackinac (AVP-13), a seaplane tender in commission from 1942 to 1947
See also
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.