Ubiquitin-specific protease 36 is an enzyme that in humans is encoded by the USP36 gene. [5] [6]

USP36
Identifiers
AliasesUSP36, DUB1, ubiquitin specific peptidase 36
External IDsOMIM: 612543; MGI: 1919594; HomoloGene: 11828; GeneCards: USP36; OMA:USP36 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_025090
NM_001321291

NM_001033528

RefSeq (protein)

NP_001308220

NP_001028700

Location (UCSC)Chr 17: 78.79 – 78.84 MbChr 11: 118.15 – 118.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a member of the ubiquitin-specific protease family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the nucleoli and deubiquitinate nucleophosmin and fibrillarin[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000055483Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033909Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–558. doi:10.1038/nrg1111. PMID 12838346. S2CID 2856065.
  6. ^ "Entrez Gene: USP36 ubiquitin specific peptidase 36".
  7. ^ Endo A, Matsumoto M, Inada T, Yamamoto A, Nakayama KI, Kitamura N, Komada M (Mar 2009). "Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36". J Cell Sci. 122 (Pt 5): 678–86. doi:10.1242/jcs.044461. PMID 19208757.

Further reading

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