USCGC Pamlico may refer to the following United States Coast Guard cutters that are named for Pamlico Sound:
- USRC Pamlico (1907), a revenue cutter in service from 1907 through 1946. From 1915 to 1946 known as USCGC Pamlico.
- USCGC Pamlico (WLIC–800), a 160–foot inland construction tender in service since 1976.
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.