u-CARE otherwise known as user-friendly Comprehensive Antibiotic resistance Repository of Escherichia coli is a database focused on the documentation of multi-drug resistant Escherichia coli (E.coli)[1][2]. This database aims to provide a tool that is easily accessible to researchers unfamiliar with bioinformatics and to medical practitioners as a reference for which antibiotic to use/not use in the treatment of an E.coli infection.[1] u-CARE is manually curated with 52 antibiotics, 107 genes, transcription factors, and SNP.[1] Information provided include resistance mechanism for the gene and summary, chemical description, and structural descriptions for the antibiotic.[1] On the antibiotic page, there is an external link linking to public databases like GO, CDD, Ecocyc, DEG, KEGG, DrugBank, Pubchem and Uniprot.[1] u-CARE can be accessed at http://www.e-bioinformatics.net/ucare..
| Content | |
|---|---|
| Description | Database focused on documentation of multi-drug resistant Escherichia coli. |
| Data types captured | E.coli |
| Organisms | Bacteria |
| Contact | |
| Research center | Sam Higginbottom University of Agriculture, Technology and Sciences |
| Primary citation | PMID 25935546 |
| Access | |
| Website | www |
| Miscellaneous | |
| Bookmarkable entities | yes |
See also
editReferences
edit- ^ a b c d e Saha, Saurav B; Uttam, Vishwas; Verma, Vivek (2015-05-02). "u-CARE: user-friendly Comprehensive Antibiotic resistance Repository ofEscherichia coli". Journal of Clinical Pathology. 68 (8): 648–651. doi:10.1136/jclinpath-2015-202927. ISSN 0021-9746. PMID 25935546. S2CID 206985362.
- ^ "AMR Curation". GitHub.