In molecular biology, the Tymovirus coat protein refers to the protein coat of a virus order, named Tymovirales. More specifically this protein signature is found only in coat proteins from the related tymoviruses. The coat protein (CP) is also known as the virion protein. The virus coat is composed of 180 copies of the coat protein arranged in an icosahedral shell.
| Tymo_coat | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 physalis mottle virus: empty capsid | |||||||||
| Identifiers | |||||||||
| Symbol | Tymo_coat | ||||||||
| Pfam | PF00983 | ||||||||
| Pfam clan | CL0055 | ||||||||
| InterPro | IPR000574 | ||||||||
| SCOP2 | 1auy / SCOPe / SUPFAM | ||||||||
| |||||||||
Function
editFundamentally, the viral coat protein functions as protection for the genetic material inside the virus, and as an aid to infecting the host cell with virus DNA. Essentially, the coat protein (CP) is a link between the genetic material and infecting the host. Since the genetic material in the virus consists of RNA the coat protein contains RNA binding sites. Additionally, the coat protein contains conserved histadine amino acid residues which help the virus to spread.[1]
Structure
editThere are three subunits named, A, B and C. It contains a beta-jelly roll motif which consists of 9 beta-strands.[2]
References
edit- ^ Bink HH, Pleij CW (2002). "RNA-protein interactions in spherical viruses". Arch Virol. 147 (12): 2261–79. doi:10.1007/s00705-002-0891-6. PMID 12491096. S2CID 29909051.
- ^ Canady MA, Larson SB, Day J, McPherson A (1996). "Crystal structure of turnip yellow mosaic virus". Nat Struct Biol. 3 (9): 771–81. doi:10.1038/nsb0996-771. PMID 8784351. S2CID 2722188.