Thiotrisescaline (T-TRIS) is a series of lesser-known phenethylamines prepared as potential psychedelic drugs. There are two isomers, 3-T-TRIS and 4-T-TRIS, each similar in structure to trisescaline with a sulfur atom in a place of a different oxygen atom. They were first synthesized by Alexander Shulgin and described in his book PiHKAL.[1][2] Very little is known about their dangers or toxicity.

T-TRIS compounds

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3-T-TRIS
 
Names
IUPAC name
2-[3,4-Diethoxy-5-(ethylsulfanyl)phenyl]ethanamine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • Key: JSWFZFXPKROBKR-UHFFFAOYSA-N
  • InChI=1S/C14H23NO2S/c1-4-16-12-9-11(7-8-15)10-13(18-6-3)14(12)17-5-2/h9-10H,4-8,15H2,1-3H
  • CCOc1cc(cc(c1OCC)SCC)CCN
Properties
C14H23NO2S
Molar mass 269.40 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Dosage: unknown
Duration: unknown
Effects: few to none
4-T-TRIS
 
Names
IUPAC name
2-[3,5-Diethoxy-4-(ethylsulfanyl)phenyl]ethanamine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • Key: VFCYKJRATPCSED-UHFFFAOYSA-N
  • InChI=1S/C14H23NO2S/c1-4-16-12-9-11(7-8-15)10-13(17-5-2)14(12)18-6-3/h9-10H,4-8,15H2,1-3H3
  • CCOc1cc(cc(c1SCC)OCC)CCN
Properties
C14H23NO2S
Molar mass 269.40 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Dosage: 240 mg
Duration: unknown
Effects: slight numbness

See also

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References

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