Talk:Triton X-100
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untitled edit
Hello, Note that the structure of TX-100 in the reference website (sigma) and the structure on the article are not the same...
What does Rohm and Haas Co have to do with Triton X-100? It seems like this sentence belongs on the entry for the Dow company. Akita86 (talk) 21:38, 11 November 2009 (UTC)
This sentence, in the first paragraph " It is very viscous at room temperature and is thus easiest to use after being gently warmed" It is not clear if it is referring to the Pluronics or the Triton X. If indeed, Pluronic, it is incorrect as these tend to increase in viscosity on heating.
Whoever wrote that was referring to Triton X-100 (also, please sign your posts) Sepia officinalis (talk) 23:32, 7 October 2010 (UTC)
What is the relevance of these sentences in the first paragraph: "It is related to the Pluronic range of detergents marketed by BASF. The pluronics are triblock copolymers of ethylene oxide and propylene oxide. The part formed from ethylene oxide is more hydrophilic than the part from propylene oxide." ?
This information is quite off-topic, and misleading (what has propylene oxide got to do with Triton X 100 at all) and has led to the misunderstanding (above) about what the viscosity referred to. 141.243.9.139 (talk) 02:47, 18 October 2010 (UTC)
Why are there chiral centers? --NikolasC1980 (talk) 20:59, 6 July 2011 (UTC)
bad intro edit
I don't have time right now, but...relation to pluronic is tenuous at best; both are members of a large, diverse family of chemicals - surfactants with PEG (aka POE aka oxyethylene) hydrophilic parts, but there are many other members of this family that are more closely related. However, think the info about rhom and has and dow are important, because surfactant nomenclature is incredibly confusing; it really helps people to have clues like that, cause many people will come to this webstie with a tradename. I know we are not a how to, but I think that wiki should offer someguidance to confused people about the plethora of diff names for the same chemcial, and the plethora of related chemicals with similar names. In any evnet, this is a pretty crappy article, will try and add some stuff this weekend when i have timeCinnamon colbert (talk) 21:05, 31 May 2011 (UTC)
Use in influenza vaccines? edit
I removed the quip "Triton X-100 appears as a final ingredient in several yearly influenza vaccines worldwide.[1]" from the article as the cited journal article only says "β-PL is widely used by the vaccine industry for vaccine preparation" and does not talk about Triton X-100 being used for vaccines but rather for inactivating the virus for ease of handling.
References
- ^ Jonges, M.; Liu, W. M.; Van Der Vries, E.; Jacobi, R.; Pronk, I.; Boog, C.; Koopmans, M.; Meijer, A.; Soethout, E. (2010). "Influenza Virus Inactivation for Studies of Antigenicity and Phenotypic Neuraminidase Inhibitor Resistance Profiling". Journal of Clinical Microbiology. 48 (3): 928–40. doi:10.1128/JCM.02045-09. PMC 2832438. PMID 20089763.
Hi together. Today I received a flu jab for the over-the-age-of-60s (Efluelda Sanofi) which contains an in the SMPC unquantified amount of Octoxinol-9. It is also not explained for what reason it is there. Would be great to have clarity in 'our' article on this topic .. Lodidol (talk) 12:47, 4 October 2021 (UTC)
Disadvantages edit
In a seminar today about cell biology, one "disadvantage" mentioned is that Triton X-100 requires an extra step in where it has to be removed from the medium again. Since I can not evaluate whether this comment is correct or not, I just added it onto the discussion page - perhaps someone else who has more knowledge in practical cell biology, could add this part into the main section IF it is correct. 2A02:8388:1641:4700:0:0:0:5 (talk) 20:00, 25 March 2017 (UTC)
Carbon numbering edit
Sigma-Aldrich lists for Triton X-100 "synonyms 4-(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol, t-Octylphenoxypolyethoxyethanol, Polyethylene glycol tert-octylphenyl ether".
Is it really a 4-(1,1,3,3-tetramethylbutyl)-phenyl group? If you count the longest chain, it's really a 4-(2,4,4-trimethylpent-2-yl)-phenoxy group. (Or maybe a 4-(2,2,4-trimethylpent-4-yl)-phenoxy group, but that probably numbers the pentane in the non-preferred direction.) This page gives the IUPAC name for the whole molecule as 2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanol. (Which is not quite right because it treats the repeating polymer shown in the sketch as if n = 1; to make it complete, change "ethanol" to "polyethoxyethanol".) Either name describes the group, but is the preferred form with "tetramethylbutyl" (with an attachment on carbon #1, which lets us say butyl instead of but-1-yl) or with "pentan-2-yl" (numbering the longest chain, puts the attachment on its carbon #2)?
There is an article for 2,2,4-Trimethylpentane, which is an isooctane. (Thus some of X-100's far-too-many synonym chemical names call the same segment "octyl", "tert-octyl", or "t-octyl".) 1,1,3,3-tetramethylbutane is a possible but non-preferred name for 2,2,4-trimethylpentane, so it is not used and has no article. - 03:44, 11 June 2019 (UTC)
More relevant guidechem links edit
Current link is: https://www.guidechem.com/reference/dic-372997.html But seems much closer chemical compounds are: https://www.guidechem.com/reference/dic-535824.html https://www.guidechem.com/reference/dic-305634.html TFJamMan (talk) 06:58, 1 May 2020 (UTC)