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Efficacy edit
quote <The time to the first dose of rescue medication required was reduced> this would be unusual in an analgesic, as it would mean, the patients who got the real drug suffered more!
Overdose edit
I feel that the article would benefit from a brief description of overdose symptoms and treatment — Preceding unsigned comment added by 107.2.190.142 (talk) 08:55, 20 December 2017 (UTC)