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°The role of nSec1 (aka Munc18) binding to Syntaxin is still under debate. The predominant model thus far posits that nSec1 binds to the closed conformation of Syntaxin and stabilizes this conformation, however more recent data suggests that nSec1 may bind to Syntaxin in other conformations as well.
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Hi there, you'd better open an account and edit the entries in Wikipedia. Unfortunately I am overengaged in many other activities, except editing in Wikipedia, that's why I couldnot update the entries that I have created. Please feel free to contribute any information you think is important, but one thing is sure - please add a REFERENCE, and possibly its PubMed id, it is easy! Danko Georgiev MD 05:59, 13 October 2006 (UTC)