Talk:Somatic evolution in cancer

Latest comment: 16 years ago by Cmaley in topic The

The

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The initial version of this page was written by members of the Santa Fe Institute working group on integrating evolutionary theory into cancer biology, including Carlo Maley, Brian Reid, John Pepper, Sabrina Spencer, Henry Heng and Tom Vincent.

There are some parts that could use some fleshing out:

  • Multilevel selection
  • Epigenetics
  • Phylogenetic analyses
  • Other forms of therapeutic resistance where the resistance has been caused by a known genetic or epigenetic (heritable) mechanism:
    • Methotrexate
    • Mutations and amplication of AR in anti-androgen therapy for prostate cancer
  • Add links to other wikipedia pages (e.g., Gefitinib? 5-flurouracil?)
  • Glossary

Carlo Maley (talk) 22:59, 16 July 2008 (UTC)Reply