Talk:Sigma factor

Latest comment: 7 years ago by 2A02:8388:1603:CB00:3AD5:47FF:FE18:CC7F in topic Sigma number?

Sigma number?

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What is the 'sigma' in sigma factor? Why the different numbers? (i.e. what is the naming convention based on?) It does not appear to be based on molecular weight as with the heat shock proteins (because sigma 70 is about 40 kDa, at least in the PDB). Is it a parameter based on ultracentrifugation? Thanks for any insight. --Dan|(talk) 16:37, 30 June 2006 (UTC)Reply

Sigma 70 is 70kDA in E.coli

This is indeed strange in PDB; for example http://www.rcsb.org/pdb/explore.do?structureId=1SIG shows about 40 kDa. But all textbooks I know, refer to sigma-70 as the name was given to indicate its molecular weight. So I can understand the confusion by Dan above. 2A02:8388:1603:CB00:3AD5:47FF:FE18:CC7F (talk) 19:28, 25 September 2017 (UTC)Reply

Merge proposal

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Regarding the proposal to merge with Sigma protein and Sigma subunit by Tameeria:

Support "Sigma protein" is completely redundant with this article and should not exist; "Sigma subunit" makes no sense without the background provided by this article. Both articles should be redirects to this page. Adrian J. Hunter(talkcontribs) 11:44, 9 December 2007 (UTC)Reply
Support What Adrian says. Spitshine (talk) 11:47, 3 March 2008 (UTC)Reply

Merged by redirecting sigma protein and sigma subunit to sigma factor. – ClockworkSoul 16:42, 21 March 2008 (UTC)Reply


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The "initiation factor" link at the beginning of this article directs to a description of translation, rather than transcription, initiation factors. —Preceding unsigned comment added by 129.137.226.9 (talk) 17:50, 22 July 2009 (UTC)Reply

Thanks for the tip. I've fixed it by delinking initiation factor and linking "transcription" to Transcription (genetics). Adrian J. Hunter(talkcontribs) 11:19, 23 July 2009 (UTC)Reply

Merge proposal: Specificity factor

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Should Specificity factor be merged into this article? I'll post further queries to appropriate people when I get the time - I just got back from vacation (if someone else wishes to do so, feel free!). Allens (talk) 02:05, 4 January 2012 (UTC)Reply