Talk:Secretin receptor

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SCTR not restricted to humans

Latest comment: 1 year ago2 comments2 people in discussion

The article begins by defining SCTR (which is what I was looking for) as "Human secretin receptor". However, SCTR is found in even in teleosts. <https://pubmed.ncbi.nlm.nih.gov/24906176/> (doi: 10.1016/j.ygcen.2014.05.025) The secretin receptor (SCTR) is a member of Class 2 subfamily B1 GPCRs and part of the PAC1/VPAC receptor subfamily. This receptor has long been known in mammals but has only recently been identified in other vertebrates including teleosts. ... All the Actinopterygii genomes analysed and the Chondrichthyes and Sarcopterygii fish possess a SCTR gene that shares conserved sequence, structure and synteny with the tetrapod homologue. ~~ Vagabond nanoda (talk) 09:20, 18 February 2023 (UTC)Reply

Fixed Thanks for your note. The HomoloGene link in the infobox (68290) also makes it clear that SCTR is found in other species besides humans. I modified the lend sentence accordingly. Boghog (talk) 10:13, 18 February 2023 (UTC)Reply

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