Genetics determining whether it's advantage or a disadvantage ?

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As can be read at http://www.wired.co.uk/article/3d-printed-skull , sclerosteosis can cause the skull to become so dense that it requires the skull to be removed. But I'm wondering whether this is always the case (I doubt it, since many people have the disease and not all require skull removal -or so I assume- ) ?

So, isn't there a gene that also makes the body change the bone width, depending on which bone it is in the body. After all, a femur is also made thicker by the body than a fingerbone. So what if the sclerosteosis-mutation (on the gene that codes for Sclerostin) is kept, yet the gene that codes for the bone thicknesses (skull) is altered ? I would assume it would then not be a problem.

KVDP (talk) 12:48, 25 June 2017 (UTC)Reply