Talk:SWI/SNF

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This article was the subject of a Wiki Education Foundation-supported course assignment, between 13 January 2020 and 6 May 2020. Further details are available on the course page. Student editor(s): Hsavino2016.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 08:30, 17 January 2022 (UTC)

File:SWI-SNF Model.jpg Nominated for speedy Deletion

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BAF complex

Should article say that the human analog is known as the BAF complex (as BAF complex roles in neurodevelopment and disorders of brain function.) ? Protein Complex Mutated in about 20% of All Cancers suggests it is. - Rod57 (talk) 23:59, 19 May 2013 (UTC)

And is that the same BAF as in Barrier-to-autointegration factor ? - Rod57 (talk) 23:50, 19 May 2013 (UTC)

Good catch. It does appear that the BAF complex is the human analog of yeast SWI/SNF. However BAF stands for "BRG1- or hbrm-associated factors".

• From: Nie Z, Yan Z, Chen EH, Sechi S, Ling C, Zhou S, Xue Y, Yang D, Murray D, Kanakubo E, Cleary ML, Wang W (2003). "Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner". Mol. Cell. Biol. 23 (8): 2942–52. doi:10.1128/MCB.23.8.2942-2952.2003. PMC 152562. PMID 12665591. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
• "Several members of the human SWI/SNF family of ATP-dependent chromatin-remodeling complexes have previously been described, including BAF (SWI/SNF-A) and PBAF (SWI/SNF-B) (BAF stands for BRG1- or hbrm-associated factors, and PBAF is for polybromo-associated BAF)"

So, yes I do think it would be appropriate to mention this in the article. Boghog (talk) 05:19, 20 May 2013 (UTC)

I went ahead and added the above in the lead. Please feel free to edit further. Boghog (talk) 05:31, 20 May 2013 (UTC)